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结构化运动方案对妊娠期糖尿病患者糖化血红蛋白和C反应蛋白的影响——一项随机对照试验

Effects of structured exercise regime on Glycosylated Hemoglobin and C reactive protein in patients with Gestational Diabetes Mellitus - A randomized controlled trial.

作者信息

Qazi Wardah Ajaz, Babur Muhammad Naveed, Malik Arshad Nawaz, Begum Ruqia

机构信息

Dr. Wardah Ajaz Qazi, PhD in Rehabilitation Sciences, Foundation University Institute of Rehabilitation Sciences, Foundation University Islamabad, Pakistan.

Prof. Dr. Muhammad Naveed Babur, PhD in Rehabilitation Sciences. Dean, Faculty of Rehabilitation Sciences, Isra University, Islamabad, Pakistan.

出版信息

Pak J Med Sci. 2020 Nov-Dec;36(7):1449-1453. doi: 10.12669/pjms.36.7.2488.

Abstract

OBJECTIVES

To evaluate the effects of structured exercise regime on Glycosylated hemoglobin and C reactive protein in patients with gestational diabetes mellitus.

METHODS

This two arm parallel randomized controlled trial was conducted at Fauji Foundation Hospital, Rawalpindi from November 2018 till December 2019 on the 54 diagnosed gestational diabetes mellitus patients (Dropped out=4 Analyzed= 50) with age 20 to 40 years and gestational age from 20 to 36 weeks. Selection was done via convenient sampling technique and randomized into two groups (n=25) by sealed envelope method. Structured exercise regime group received combination of moderate intensity aerobics, stabilization and pelvic floor muscles exercises twice a week for 5 weeks (40 min per session) along with dietary and medical interventions while control group received only medical and dietary interventions with postural education. Demographics, glycosylated hemoglobin and C reactive protein were recorded at baseline then after 5 weeks of intervention. Analysis was done by SPSS 20.

RESULTS

Mean age was 35.92 ± 5.24 years in control group while 34.36 ± 5.21 years in interventional group. Between group analysis for HbA1c showed no significant difference at base line (p >0.05) but showed significant difference (p <0.05) after five weeks' interventions. Similarly, for C reactive protein both groups showed no significant difference (p >0.05) at baseline but after five weeks of interventions showed significant difference (p<0.05).

CONCLUSION

Structured exercise regime helps in reducing values of glycosylated hemoglobin and C reactive protein in patients with gestational diabetes mellitus.

摘要

目的

评估结构化运动方案对妊娠期糖尿病患者糖化血红蛋白和C反应蛋白的影响。

方法

本双臂平行随机对照试验于2018年11月至2019年12月在拉瓦尔品第的法吉基金会医院对54例确诊为妊娠期糖尿病的患者(退出=4例,分析=50例)进行,患者年龄在20至40岁之间,孕周在20至36周之间。通过方便抽样技术进行选择,并采用密封信封法随机分为两组(n=25)。结构化运动方案组每周进行两次中等强度有氧运动、稳定训练和盆底肌肉锻炼,持续5周(每次40分钟),同时进行饮食和药物干预,而对照组仅接受药物和饮食干预以及姿势教育。在基线时以及干预5周后记录人口统计学数据、糖化血红蛋白和C反应蛋白。使用SPSS 20进行分析。

结果

对照组的平均年龄为35.92±5.24岁,干预组为34.36±5.21岁。两组间糖化血红蛋白的组间分析在基线时无显著差异(p>0.05),但在干预5周后有显著差异(p<0.05)。同样,C反应蛋白在基线时两组均无显著差异(p>0.05),但在干预5周后有显著差异(p<0.05)。

结论

结构化运动方案有助于降低妊娠期糖尿病患者的糖化血红蛋白和C反应蛋白值。

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