Majeed Farrukh, Yar Talay, Alsunni Ahmed A, AlHawaj Ali F, AlRahim Ahmed A
Dr. Farrukh Majeed, FCPS. Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
Dr. Talay Yar, PhD. Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
Pak J Med Sci. 2020 Nov-Dec;36(7):1590-1595. doi: 10.12669/pjms.36.7.2419.
There is lack of evidence exploring sympathetic effect by baroreceptor sensitivity in obese consuming energy drink. The purpose of this study was to investigate the acute effect of energy drink on individuals baroreceptor sensitivity in young healthy normal weight and overweight/obese males.
This cross-sectional study was performed in the Department of Physiology, Imam Abdulrahman Bin Faisal University, Kingdom of Saudi Arabia. After getting ethical approval, 25 male participants were recruited by convenient sampling and informed consent was obtained. Participants were grouped into normal weight and overweight/obese on basis of body mass index. Finger arterial blood pressure was recorded with Finometer® at baseline, 30min and 60 minutes in the post-energy drink period and baroreceptor sensitivity was calculated. As data was not normally distributed it was log transformed.
The baseline baroreceptor sensitivity was lower (P<0.05) in overweight/obese compared to normal weight participants. Baroreceptor sensitivity reduced significantly (P<0.05) at 60 minutes after energy drink consumption in the whole cohort of both normal weight and overweight/obese. Baroreceptor sensitivity remained lower in overweight/obese compared to normal weight at 60min but the difference was not significant.
Consumption of energy drink acutely reduced baroreceptor sensitivity in both normal weight and obese young healthy males with an earlier onset of effect in overweight/obese indicating enhanced sympathetic activity. Energy drinks consumption could place the obese in a more vulnerable state to hypertension and arrhythmia.
缺乏证据探讨能量饮料对肥胖者压力感受器敏感性的交感神经效应。本研究的目的是调查能量饮料对年轻健康正常体重和超重/肥胖男性个体压力感受器敏感性的急性影响。
这项横断面研究在沙特阿拉伯王国伊玛目阿卜杜勒拉赫曼·本·费萨尔大学的生理学系进行。获得伦理批准后，通过方便抽样招募了25名男性参与者，并获得了知情同意。根据体重指数将参与者分为正常体重组和超重/肥胖组。在饮用能量饮料后的基线、30分钟和60分钟，使用Finometer®记录手指动脉血压，并计算压力感受器敏感性。由于数据呈非正态分布，因此进行对数转换。
与正常体重参与者相比，超重/肥胖者的基线压力感受器敏感性较低（P<0.05）。在正常体重和超重/肥胖的整个队列中，饮用能量饮料60分钟后，压力感受器敏感性显著降低（P<0.05）。在60分钟时，超重/肥胖者的压力感受器敏感性仍低于正常体重者，但差异不显著。
饮用能量饮料会使正常体重和肥胖的年轻健康男性的压力感受器敏感性急性降低，超重/肥胖者的效应起效更早，表明交感神经活动增强。饮用能量饮料可能会使肥胖者更容易患高血压和心律失常。
