Department of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, Pisa, Italy.
Department of Health Science, University of Milan, Milan, Italy.
Pediatr Allergy Immunol. 2020 Nov;31 Suppl 26:43-45. doi: 10.1111/pai.13364.
The use of probiotic supplements might change the composition of the intestinal flora of children, subsequently modulating the immune system's reactivity. The effects of probiotic administration for the prevention/treatment of allergic diseases and atopic dermatitis, in particular, are still so controversial that no definitive recommendation can be made at this stage. Differences in strain specificity, timing, and length of administration all contribute to diversifying the conclusions of this review.
益生菌补充剂的使用可能会改变儿童肠道菌群的组成，从而调节免疫系统的反应性。益生菌用于预防/治疗过敏性疾病和特应性皮炎的效果仍存在争议，因此现阶段无法给出明确的建议。菌株特异性、使用时机和使用时间长短的差异都导致了这篇综述的结论多样化。
