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青少年患者同时患有克罗恩病和多发性大动脉炎。

Simultaneous Presentation of Crohn's Disease and Takayasu Arteritis in a Teenage Patient.

机构信息

Emory University, Atlanta, GA, USA.

Children's Healthcare of Atlanta, Atlanta, GA, USA.

出版信息

J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620977317. doi: 10.1177/2324709620977317.

Abstract

A 14-year-old female with no significant medical history presented with hypertensive urgency, in the setting of 4 to 6 weeks of diarrhea, abdominal pain, headaches, anemia, weight loss, and high blood pressures. Her evaluation revealed signs of a systemic inflammatory process that was most suspicious for inflammatory bowel disease. However, when her hypertension was evaluated with a renal Doppler ultrasound, there were signs of narrowing, stenosis, and hypoplasia that led to a diagnostic angiogram of the abdominal aorta. Full body positron emission tomography scan revealed multiple areas of stenosis and aortic thickening with enhancement compatible with Takayasu arteritis. She received prednisone, methotrexate, and infliximab with marked improvement in her clinical symptoms and inflammatory markers.

摘要

一位 14 岁的女性,既往无重大病史,因高血压急症就诊,伴有 4 至 6 周的腹泻、腹痛、头痛、贫血、体重减轻和高血压。她的评估显示出全身炎症过程的迹象,最可疑的是炎症性肠病。然而,当对她的高血压进行肾多普勒超声检查时,发现有狭窄、狭窄和发育不良的迹象,导致进行腹部主动脉的诊断性血管造影。全身正电子发射断层扫描显示多处狭窄和主动脉增厚,增强扫描与 Takayasu 动脉炎相符。她接受了泼尼松、甲氨蝶呤和英夫利昔单抗治疗,临床症状和炎症标志物明显改善。

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