Department of Pediatrics, National and Kapodistrian University of Athens, "ATTIKON" General Hospital, 1 Rimini Str, Chaidari, 12462, Athens, Greece.
Department of Radiology, National and Kapodistrian University of Athens, "ATTIKON" General Hospital, 1 Rimini Str, Chaidari, 12462, Athens, Greece.
Rheumatol Int. 2022 Mar;42(3):563-570. doi: 10.1007/s00296-021-04869-5. Epub 2021 Apr 27.
Crohn's disease (CD) and Takayasu arteritis (TA) are two distinct clinical entities. Τhe likelihood of both diseases coexisting is low, and although CD co-occurs with all types of vasculitis, TA is the most common subtype. Herein, the case of a 15-year-old female, diagnosed with TA following an initial diagnosis of CD, is reported. A review of the literature, including a systemic review of the case reports and case series of children and adolescents up to the age of 21, with both CD and TA, follows the case description. In total, 28 cases of TA and CD were retrieved. The median age of patients was 14.8 years, they were mostly females (72%) and the median time between the two diagnoses was 3.7 years. In the majority of cases, CD was diagnosed first and TA followed. Computed tomography angiography and magnetic resonance angiography were the preferred imaging modalities to assist diagnosis.
克罗恩病(CD)和 Takayasu 动脉炎(TA)是两种截然不同的临床实体。这两种疾病同时存在的可能性很低,虽然 CD 与所有类型的血管炎并存,但 TA 是最常见的亚型。本文报告了一例 15 岁女性,最初诊断为 CD,后诊断为 TA。在病例描述之后,对文献进行了回顾,包括对儿童和青少年(21 岁以下)的病例报告和病例系列的系统综述,这些病例同时患有 CD 和 TA。共检索到 28 例 TA 和 CD。患者的中位年龄为 14.8 岁,大多数为女性(72%),两次诊断之间的中位时间为 3.7 年。在大多数情况下,首先诊断出 CD,然后诊断出 TA。计算机断层血管造影和磁共振血管造影是辅助诊断的首选成像方式。