Trauma Nursing Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
BMC Pregnancy Childbirth. 2020 Nov 25;20(1):728. doi: 10.1186/s12884-020-03417-6.
The optimal objective of infertility treatments is to increase pregnancy rate. The aim of this study was to assess the effectiveness of a collaborative counseling program on pregnancy rate in women undergoing in vitro treatment.
This was a parallel group randomized trial on a sample of 60 women attending to an infertility research center affiliated to Mashhad University of Medical Sciences for fertility treatment. Women were randomly assigned to an intervention or a control group. Then, a five-session program offered to the intervention group while the control group received nothing expect the usual care. The primary outcome for the study was positive pregnancy test at the end of study. Statistical analyses including independent samples t-test were performed to explore the data.
The outcome analysis showed that there were no significant differences in pregnancy rate between the intervention and the control groups (P = 0.298). Also, there were no significant differences in follicle and embryo numbers between two groups. However, a significant difference was observed between two groups in terms of oocyte numbers where the intervention group had more oocyte (P = 0.014).
Overall the findings indicated that the collaborative infertility counseling did not improve treatment success in infertile women undergoing in vitro fertilization.
IRCT201110267915N1. Registered 2014.07.25-Retrospectively registered ( http://en.irct.ir/trial/8359 ).
不孕治疗的最佳目标是提高妊娠率。本研究旨在评估协作咨询方案对接受体外治疗的女性妊娠率的有效性。
这是一项平行组随机试验，纳入了 60 名在马什哈德医科大学不孕研究中心接受生育治疗的女性。将女性随机分配到干预组或对照组。然后，为干预组提供五次课程计划，而对照组除了常规护理外什么也不接受。研究的主要结局是研究结束时的妊娠试验阳性。进行了独立样本 t 检验等统计分析来探索数据。
结果分析表明，干预组和对照组的妊娠率没有显著差异（P=0.298）。此外，两组的卵泡和胚胎数量没有显著差异。然而，两组之间的卵母细胞数量存在显著差异，干预组的卵母细胞数量更多（P=0.014）。
总体而言，研究结果表明，协作性不孕咨询并没有提高接受体外受精的不孕女性的治疗成功率。
IRCT201110267915N1。注册于 2014 年 7 月 25 日-回顾性注册（http://en.irct.ir/trial/8359）。
