Banerjee Amit, Gandhi Arohi B, Antony Ishan, Alexander Josh, Hisbulla Mohamed, Kannichamy Vishmita, Kaleem Ifrah, Mishra Vinayak, Khan Safeera
Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Cureus. 2020 Oct 22;12(10):e11097. doi: 10.7759/cureus.11097.
Legalizing cannabis use in various states in the United States has caused increased substance abuse, mostly among young people. There are very little data focussing on marijuana use and myocardial infarction (MI) incidence. The objective of the study is to analyze the published papers for cannabis-induced MI and derive a strong relation between cannabis use and MI and understand the pathophysiology. An online search was conducted in PubMed, Google Scholar, and PubMed Central to find relevant publications examining patients who developed MI due to cannabis use. Out of 32 articles that were identified for this review, 17 are case reports, one is a letter to the editor, eight are observational studies, and six are review articles. Many studies have proposed different mechanisms by which cannabis affects the body. Our study shows that marijuana can precipitate MI even if it is used for the first time. Limited data is available to comment on the mortality of patients after cannabis-induced MI. These findings highlight the necessity for public awareness to prevent the ill-effects of cannabis, especially for teenagers and older people.
美国多个州将大麻使用合法化导致药物滥用情况增加，其中年轻人受影响最大。目前聚焦于大麻使用与心肌梗死（MI）发病率的相关数据非常少。本研究的目的是分析已发表的关于大麻诱发心肌梗死的论文，得出大麻使用与心肌梗死之间的紧密关系，并了解其病理生理学。我们在PubMed、谷歌学术和PubMed Central上进行了在线搜索，以查找研究因使用大麻而发生心肌梗死患者的相关出版物。在本次综述确定的32篇文章中，17篇为病例报告，1篇为给编辑的信，8篇为观察性研究，6篇为综述文章。许多研究提出了大麻影响身体的不同机制。我们的研究表明，大麻即使首次使用也会引发心肌梗死。关于大麻诱发心肌梗死后患者死亡率的可用数据有限。这些发现凸显了提高公众意识以预防大麻不良影响的必要性，尤其是对青少年和老年人而言。
