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无需再次阻断主动脉修复室间隔缺损残余分流:一种安全有效的外科手术方法。

Revising ventricular septal defect residual shunts without aortic re-cross-clamping: a safe and effective surgical procedure.

作者信息

Cao Zhongming, Chai Yunfei, Liu Jian, Liu Shiguo, Wei Jinfeng, Liang Jiexian, Zhuang Jian, Wang Sheng, Xu Gang

机构信息

Department of Anesthesiology, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences, Guangzhou, China.

Department of Cardiac Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences, Guangzhou, China.

出版信息

Ann Transl Med. 2020 Sep;8(18):1134. doi: 10.21037/atm-20-5041.

Abstract

BACKGROUND

The conventional approach to revising a residual shunt following ventricular septal defect (VSD) closure is to re-occlude the aorta and repair the residual shunt under cardioplegic arrest. The present study evaluated the safety and effectiveness of a new approach for revising residual shunts following VSD repair without re-occluding the aorta. This approach is known as on beating heart surgery.

METHODS

This retrospective study included 80 pediatric patients who underwent surgical closure of a simple VSD. Residual shunts larger than 2 mm were intraoperatively detected by transesophageal echocardiography (TEE) and these patients received immediate reintervention. Of the patients, 37 received on beating heart surgery without aortic cross-clamping (Group A) and 43 patients were operated on with aortic cross-clamping and cardioplegia (Group B).

RESULTS

Residual VSD closures were successfully performed in all patients. Group A had significantly shorter aortic cross-clamp times (P<0.0001), significantly shorter CPB times (P<0.01), a lower incidence of prolonged ventilation (>6 hours) (P=0.04), a lower incidence of prolonged intensive care unit (ICU) stay (ICU stay >1 day) (P=0.02), and reduced in-hospital expenses (P<0.0001) compared with Group B. There was no significant difference in the incidence of recurrent residual shunts (P=0.96), prolonged postoperative hospital stay (>5 days) (P=0.24), or the incidence of perioperative complications (P=0.81) between the groups.

CONCLUSIONS

On beating heart surgery is a safe and effective approach for the closure of residual VSDs and is significantly associated with a lower incidence of prolonged ventilation, a lower incidence of prolonged ICU stay, and reduced in-hospital expenses.

摘要

背景

室间隔缺损(VSD)封堵术后残余分流的传统修复方法是重新阻断主动脉,并在心脏停搏下修复残余分流。本研究评估了一种不重新阻断主动脉修复VSD术后残余分流的新方法的安全性和有效性。这种方法被称为不停跳心脏手术。

方法

这项回顾性研究纳入了80例接受单纯VSD手术封堵的儿科患者。术中经食管超声心动图(TEE)检测到残余分流大于2mm的患者立即接受再次干预。其中,37例患者接受了不停跳心脏手术且未进行主动脉阻断(A组),43例患者接受了主动脉阻断和心脏停搏手术(B组)。

结果

所有患者的残余VSD均成功封堵。与B组相比,A组的主动脉阻断时间显著缩短(P<0.0001),体外循环时间显著缩短(P<0.01),长时间机械通气(>6小时)的发生率较低(P=0.04),重症监护病房(ICU)长时间住院(ICU住院>1天)的发生率较低(P=0.02),住院费用降低(P<0.0001)。两组之间复发残余分流的发生率(P=0.96)、术后长时间住院(>5天)的发生率(P=0.24)或围手术期并发症的发生率(P=0.81)无显著差异。

结论

不停跳心脏手术是封堵残余VSD的一种安全有效的方法,与长时间机械通气发生率较低、ICU长时间住院发生率较低以及住院费用降低显著相关。

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