Cao Zhongming, Chai Yunfei, Liu Jian, Liu Shiguo, Wei Jinfeng, Liang Jiexian, Zhuang Jian, Wang Sheng, Xu Gang
Department of Anesthesiology, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences, Guangzhou, China.
Department of Cardiac Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences, Guangzhou, China.
Ann Transl Med. 2020 Sep;8(18):1134. doi: 10.21037/atm-20-5041.
The conventional approach to revising a residual shunt following ventricular septal defect (VSD) closure is to re-occlude the aorta and repair the residual shunt under cardioplegic arrest. The present study evaluated the safety and effectiveness of a new approach for revising residual shunts following VSD repair without re-occluding the aorta. This approach is known as on beating heart surgery.
This retrospective study included 80 pediatric patients who underwent surgical closure of a simple VSD. Residual shunts larger than 2 mm were intraoperatively detected by transesophageal echocardiography (TEE) and these patients received immediate reintervention. Of the patients, 37 received on beating heart surgery without aortic cross-clamping (Group A) and 43 patients were operated on with aortic cross-clamping and cardioplegia (Group B).
Residual VSD closures were successfully performed in all patients. Group A had significantly shorter aortic cross-clamp times (P<0.0001), significantly shorter CPB times (P<0.01), a lower incidence of prolonged ventilation (>6 hours) (P=0.04), a lower incidence of prolonged intensive care unit (ICU) stay (ICU stay >1 day) (P=0.02), and reduced in-hospital expenses (P<0.0001) compared with Group B. There was no significant difference in the incidence of recurrent residual shunts (P=0.96), prolonged postoperative hospital stay (>5 days) (P=0.24), or the incidence of perioperative complications (P=0.81) between the groups.
On beating heart surgery is a safe and effective approach for the closure of residual VSDs and is significantly associated with a lower incidence of prolonged ventilation, a lower incidence of prolonged ICU stay, and reduced in-hospital expenses.
室间隔缺损(VSD)封堵术后残余分流的传统修复方法是重新阻断主动脉,并在心脏停搏下修复残余分流。本研究评估了一种不重新阻断主动脉修复VSD术后残余分流的新方法的安全性和有效性。这种方法被称为不停跳心脏手术。
这项回顾性研究纳入了80例接受单纯VSD手术封堵的儿科患者。术中经食管超声心动图(TEE)检测到残余分流大于2mm的患者立即接受再次干预。其中,37例患者接受了不停跳心脏手术且未进行主动脉阻断(A组),43例患者接受了主动脉阻断和心脏停搏手术(B组)。
所有患者的残余VSD均成功封堵。与B组相比,A组的主动脉阻断时间显著缩短(P<0.0001),体外循环时间显著缩短(P<0.01),长时间机械通气(>6小时)的发生率较低(P=0.04),重症监护病房(ICU)长时间住院(ICU住院>1天)的发生率较低(P=0.02),住院费用降低(P<0.0001)。两组之间复发残余分流的发生率(P=0.96)、术后长时间住院(>5天)的发生率(P=0.24)或围手术期并发症的发生率(P=0.81)无显著差异。
不停跳心脏手术是封堵残余VSD的一种安全有效的方法,与长时间机械通气发生率较低、ICU长时间住院发生率较低以及住院费用降低显著相关。