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[一款用于结直肠息肉样病变诊断及特征分析的软件在临床研究中的构建与应用]

[Structuring and use in clinical research of a software for the diagnosis and features of polypoid lesions of the colorectum].

作者信息

Bellomi M, Pestalozza M A, Cozzi G, Bellegotti L, Graziano M, Gardani G, Severini A

机构信息

Istituto di Scienze Radiologiche, Università, Milano.

出版信息

Radiol Med. 1987 Dec;74(6):543-5.

PMID:3324196
Abstract

Double contrast enema and endoscopy are very important in the diagnosis of adenomas and early cancer of the colon and rectum. These exams can not only detect the presence, but also suggest the histologic diagnosis, of polypoid lesions of the colon. An Olivetti M24 Personal Computer was used to create a software to study the results obtained by double contrast enema, and to compare them with endoscopy and pathology. The data base is formed by 7 files: one anagraphic, 3 collecting the characteristics of the diagnosis--namely the radiologic, the endoscopic and the pathologic one-- and 3 multiple files featuring each lesion, as defined by the three diagnostic techniques. The software allows to evaluate the different lesions that can be detected by the three techniques in the same patient and to compare the diagnosis of presence to the morphologic features of each lesion. False negatives and false positives of each technique are easily recognized. It is also possible to characterize the single morphologic feature leading the radiologist and/or the endoscopist to express an opinion about the histologic diagnosis of each lesion and to compare them with pathological features. The first experience in clinical use of the software, in the analysis of the characters of 336 lesions in 218 patients, is described.

摘要

双重对比灌肠造影和内镜检查在结肠和直肠腺瘤及早期癌的诊断中非常重要。这些检查不仅能检测结肠息肉样病变的存在,还能提示其组织学诊断。使用Olivetti M24个人计算机创建了一个软件,用于研究双重对比灌肠造影获得的结果,并将其与内镜检查和病理学结果进行比较。数据库由7个文件组成:一个是患者信息文件,3个收集诊断特征——即放射学、内镜和病理学特征——还有3个多文件,分别记录三种诊断技术所定义的每个病变的特征。该软件可以评估同一患者中三种技术能够检测到的不同病变,并将存在性诊断与每个病变的形态学特征进行比较。每种技术的假阴性和假阳性很容易识别。还可以对导致放射科医生和/或内镜医生对每个病变的组织学诊断发表意见的单一形态学特征进行描述,并将其与病理学特征进行比较。本文描述了该软件在临床应用中的首次经验,即对218例患者的336个病变特征进行分析。

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