Department of Neurosurgery, Houston Methodist Hospital 6560 Fannin St Suite 900, Houston, TX, 77030, United States.
Curr Neurovasc Res. 2020;17(5):754-759. doi: 10.2174/1567202617999201125202131.
Since the introduction of endovascular methods to treat cerebral aneurysms, several technical advances have allowed a greater number of aneurysms to be treated endovascularly as opposed to open surgical clipping. These include flow diverting stents, which do not utilize coils and instead treat aneurysms by acting as an "internal bypass." We sought to investigate whether flow diversion is replacing coiling at our institution.
A retrospective chart review on five years of data was conducted to investigate the possible increasing use of flow diversion devices compared to traditional simple or stent-assisted coiling.
Over five years, the population revealed a trend toward an increased proportion of female patients, increased frequency of basilar tip and internal carotid artery (ICA) aneurysm location, increased hospital volume, and increased volume of patients treated by dual-trained neurosurgeons over interventional radiologists. Patients were stratified by aneurysm location and statistically significant differences were observed. Flow diversion devices were used with increasing frequency when treating aneurysms arising from the proximal internal carotid artery (Odds ratio (OR)=1.24, 95% CI: 1.02-1.50; p = 0.03), and middle cerebral artery (OR=2.60, 95% CI: 1.38-4.88; p = 0.003). Distal internal carotid artery aneurysm location came close to achieving statistical significance (OR=1.3, 95% CI: 0.99-1.72; p = 0.063).
In our single center experience at Houston Methodist Hospital, flow diversion devices are being used more frequently for aneurysms arising from the proximal ICA, MCA, and likely distal ICA (though this third location barely failed to achieve statistical significance.
自采用血管内方法治疗脑动脉瘤以来,多项技术进步使得更多的动脉瘤能够通过血管内治疗而不是开颅夹闭来治疗。其中包括血流导向支架,它不使用线圈,而是通过充当“内部旁路”来治疗动脉瘤。我们试图研究在我们的机构中血流导向是否正在取代线圈。
对五年的数据进行回顾性图表审查,以调查与传统的单纯或支架辅助线圈相比,血流导向装置的使用是否有增加的趋势。
在五年期间,患者群体中女性患者的比例呈上升趋势,基底尖和颈内动脉(ICA)动脉瘤的位置频率增加,医院容量增加,接受双培训的神经外科医生治疗的患者数量增加而介入放射科医生。患者根据动脉瘤位置进行分层,观察到统计学显著差异。当治疗起源于近端颈内动脉(比值比(OR)=1.24,95%置信区间:1.02-1.50;p=0.03)和大脑中动脉(OR=2.60,95%置信区间:1.38-4.88;p=0.003)的动脉瘤时,血流导向装置的使用频率增加。远端颈内动脉动脉瘤位置接近统计学意义(OR=1.3,95%置信区间:0.99-1.72;p=0.063)。
在我们休斯顿卫理公会医院的单中心经验中,血流导向装置越来越多地用于治疗起源于近端 ICA、MCA 的动脉瘤,可能还有远端 ICA(尽管这第三个位置几乎没有达到统计学意义。