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Sex Differences in Lopinavir Concentrations and Occurrence of Marked QTc Prolongation Episodes in Patients with COVID-19.

作者信息

Marzolini Catia, Stader Felix, Leuppi-Taegtmeyer Anne, Stoeckle Marcel, Battegay Manuel, Sendi Parham

机构信息

Division of Infectious Diseases, Hospital Epidemiology, University Hospital Basel and University of Basel, Basel, Switzerland.

Department of Clinical Pharmacology and Toxicology, University Hospital Basel and University of Basel, Basel, Switzerland.

出版信息

Drug Saf. 2021 Feb;44(2):255-257. doi: 10.1007/s40264-020-01025-z. Epub 2020 Nov 27.

DOI:10.1007/s40264-020-01025-z
PMID:33245507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7694584/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8120/7694584/00da1c32f3d6/40264_2020_1025_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8120/7694584/00da1c32f3d6/40264_2020_1025_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8120/7694584/00da1c32f3d6/40264_2020_1025_Fig1_HTML.jpg

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2
Potential Influence of Menstrual Status and Sex Hormones on Female Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Cross-sectional Multicenter Study in Wuhan, China.月经状态和性激素对女性严重急性呼吸综合征冠状病毒 2 感染的潜在影响：中国武汉的一项横断面多中心研究。
Clin Infect Dis. 2021 May 4;72(9):e240-e248. doi: 10.1093/cid/ciaa1022.
3
Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations.
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Antimicrob Agents Chemother. 2020 Aug 20;64(9). doi: 10.1128/AAC.01177-20.
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Am J Physiol Lung Cell Mol Physiol. 2020 Jun 1;318(6):L1280-L1281. doi: 10.1152/ajplung.00153.2020. Epub 2020 May 20.
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