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STAT3 and TP53 mutations associate with poor prognosis in anaplastic large cell lymphoma.

作者信息

Lobello Cosimo, Tichy Boris, Bystry Vojtech, Radova Lenka, Filip Daniel, Mraz Marek, Montes-Mojarro Ivonne-Aidee, Prokoph Nina, Larose Hugo, Liang Huan-Chang, Sharma Geeta G, Mologni Luca, Belada David, Kamaradova Katerina, Fend Falko, Gambacorti-Passerini Carlo, Merkel Olaf, Turner Suzanne D, Janikova Andrea, Pospisilova Sarka

机构信息

Center of Molecular Medicine, Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.

Department of Internal Medicine-Hematology and Oncology, University Hospital Brno and Medical Faculty MU, Brno, Czech Republic.

出版信息

Leukemia. 2021 May;35(5):1500-1505. doi: 10.1038/s41375-020-01093-1. Epub 2020 Nov 27.

DOI:10.1038/s41375-020-01093-1
PMID:33247178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8102183/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68d4/8102183/e742a2eb313b/41375_2020_1093_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68d4/8102183/bc7de6611d8a/41375_2020_1093_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68d4/8102183/e742a2eb313b/41375_2020_1093_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68d4/8102183/bc7de6611d8a/41375_2020_1093_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68d4/8102183/e742a2eb313b/41375_2020_1093_Fig2_HTML.jpg

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Blood. 2020 Jan 30;135(5):360-370. doi: 10.1182/blood.2019001904.
在使用巴瑞替尼治疗特应性皮炎期间发生的伴有TP53突变的ALK阴性间变性大细胞淋巴瘤——病例报告
J Clin Exp Hematop. 2025;65(1):55-61. doi: 10.3960/jslrt.24048.
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TP53 deletion is associated with poor survival of adult ALK-positive ALCL patients receiving CHOP-based chemotherapy.TP53缺失与接受基于CHOP化疗的成年ALK阳性间变性大细胞淋巴瘤（ALCL）患者的不良生存相关。
Ann Hematol. 2025 Mar;104(3):1801-1806. doi: 10.1007/s00277-025-06297-y. Epub 2025 Mar 10.
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Comprehensive genomic analysis reveals molecular heterogeneity in pediatric ALK-positive anaplastic large cell lymphoma.全面基因组分析揭示儿童ALK阳性间变性大细胞淋巴瘤的分子异质性。
Leukemia. 2025 Jan;39(1):199-210. doi: 10.1038/s41375-024-02468-4. Epub 2024 Nov 26.
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