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2011 - 2016年美国用于特应性皮炎的抗组胺药处方趋势

US Prescription trends of antihistamines for atopic dermatitis, 2011-2016.

作者信息

Garg Swati, Zhao Jeffrey, Tegtmeyer Kyle, Shah Parth, Lio Peter A

机构信息

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

Pediatr Dermatol. 2021 Jan;38(1):324-326. doi: 10.1111/pde.14445. Epub 2020 Nov 27.

DOI:10.1111/pde.14445
PMID:33247474
Abstract

Antihistamine use for primary treatment of atopic dermatitis (AD) is not recommended, but current guidelines state that sedating antihistamines are favored over non-sedating antihistamines for relief of burdensome pruritus. We analyzed the National Ambulatory Medical Care Survey data to compare use of antihistamines between dermatologists and non-dermatologists. Overall, dermatologists are more likely to prescribe sedating than non-sedating antihistamines when compared to non-dermatologists (P < .001, δ  = 0.45). Patients under 21 years old (P = .03, δ  = 0.10) and Black patients (P < .001, δ  = 0.19) were also more likely to receive sedating antihistamines than non-sedating antihistamines. These findings highlight the differential prescribing practices for atopic dermatitis among physicians.

摘要

不推荐使用抗组胺药作为特应性皮炎(AD)的主要治疗方法,但当前指南指出,在缓解严重瘙痒方面,镇静性抗组胺药比非镇静性抗组胺药更受青睐。我们分析了国家门诊医疗调查数据,以比较皮肤科医生和非皮肤科医生对抗组胺药的使用情况。总体而言,与非皮肤科医生相比,皮肤科医生更有可能开具镇静性抗组胺药而非非镇静性抗组胺药(P <.001,δ = 0.45)。21岁以下的患者(P = 0.03,δ = 0.10)和黑人患者(P <.001,δ = 0.19)也比非镇静性抗组胺药更有可能接受镇静性抗组胺药。这些发现突出了医生在特应性皮炎处方方面的差异。

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