Gupta Udita, Prakash Anupam, Sachdeva Sonali, Pangtey Ghan Shyam, Khosla Akshita, Aggarwal Ramesh, Sud Ritika, Margekar Shubha Laxmi
Clinical Research Associate, Department of Medicine, Lady Hardinge Medical College and Associated Hospitals, New Delhi.
Professor, Department of Medicine, Lady Hardinge Medical College and Associated Hospitals, New Delhi.
J Assoc Physicians India. 2020 Dec;68(12):69-72.
Coronavirus disease 2019 (COVID-19), causes serious respiratory illness manifesting as pneumonia, adult respiratory distress syndrome and respiratory failure. Amidst the rising number of cases and deaths, it is imperative to not forget Tuberculosis (TB) which is another pandemic existing since centuries. There could be dire consequences for tuberculosis patients globally especially in low and middle income countries with a high burden of disease and overwhelmed health care systems. Tuberculosis is still the leading infectious killer worldwide, and therefore, it is crucial to reflect on the interaction between the two diseases. Evidence suggests that both COVID-19 and tuberculosis have a synergistic relationship, boosting detrimental effect of each other, disrupting existing health care models, and also worsening the clinical outcomes in terms of morbidity and mortality. This review aims to draw attention towards this pertinent clinical issue, and tries to unravel the intricate relationship between COVID-19 and tuberculosis, as also the role of BCG vaccination to combat the COVID-19 pandemic.
2019冠状病毒病（COVID-19）会引发严重的呼吸系统疾病，表现为肺炎、成人呼吸窘迫综合征和呼吸衰竭。在病例数和死亡人数不断上升的情况下，切不可忘记结核病，它已存在数百年，也是一场大流行病。全球的结核病患者可能会面临严重后果，尤其是在疾病负担高且医疗系统不堪重负的低收入和中等收入国家。结核病仍是全球主要的感染性杀手，因此，思考这两种疾病之间的相互作用至关重要。有证据表明，COVID-19和结核病存在协同关系，会增强彼此的有害影响，扰乱现有的医疗模式，还会在发病率和死亡率方面恶化临床结果。本综述旨在引起人们对这一相关临床问题的关注，并试图阐明COVID-19与结核病之间的复杂关系，以及卡介苗接种在抗击COVID-19大流行中的作用。
