Institute for Health Metrics; Department of Health Metrics Sciences, University of Washington, Seattle, WA, USA.
Infectious Diseases Research Collaboration, Kampala, Uganda.
Trends Parasitol. 2021 Mar;37(3):185-194. doi: 10.1016/j.pt.2020.10.011. Epub 2020 Nov 26.
In vector control, it is widely accepted that killing adult mosquitoes would sharply reduce the proportion of old mosquitoes and cause the greatest changes to malaria transmission. The principle is based on a mathematical model of the sporozoite rate (the proportion of infective mosquitoes) that emphasized changes in mosquito age. Killing adult mosquitoes also reduces mosquito population densities, which are directly proportional to human biting rates (the number of bites, per person, per day). Eect sizes of vector control can be compared using sporozoite rates and human biting rates, which are commonly measured. We argue that human biting rates convey more use- ful information for planning, monitoring and evaluating vector control, and operational research should focus on understanding mosquito ecology.
在病媒控制中，人们普遍认为杀死成蚊会大幅降低老龄蚊比例，从而对疟疾传播造成最大影响。这一原理基于疟原虫感染率（感染性蚊子比例）的数学模型，该模型强调了蚊子年龄的变化。杀死成蚊还会降低蚊密度，蚊密度与人类叮咬率（每人每天的叮咬次数）直接相关。可以使用普遍测量的疟原虫感染率和人类叮咬率来比较病媒控制的效果。我们认为，人类叮咬率为规划、监测和评估病媒控制提供了更有用的信息，而应将运营研究重点放在了解蚊子生态上。
