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内镜检查发现极幼龄婴儿患有假膜性结肠炎。

Infection in a Very Young Infant with Pseudomembranous Colitis Noted on Endoscopy.

作者信息

Tibesar Eric

机构信息

Pediatric Gastroenterology, Peyton Manning Children's Hospital, Indianapolis, Indiana, USA.

出版信息

Case Rep Gastroenterol. 2020 Oct 27;14(3):522-526. doi: 10.1159/000508916. eCollection 2020 Sep-Dec.

DOI:10.1159/000508916
PMID:33250692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7670329/
Abstract

infection rates have been rising within the last decade and more pediatric patients have been suffering from this type of infection. However, this bacterium is a well-known contaminant in the normal flora of the colon in patients under the age of 2 years, and therefore consensus guidelines have recommended against routine testing for this infection, unless clinically indicated. We present here a case of a very young infant who presented with symptoms of food refusal, poor weight gain, abdominal distention, and colitis noted on imaging. Endoscopic evaluation demonstrated the presence of pseudomembranous colitis, so the patient was treated with antibiotics against and recovered fully. This case demonstrates the importance of keeping colitis in your differential diagnosis, even at a very young age.

摘要

在过去十年中,感染率一直在上升,越来越多的儿科患者受到这种类型的感染。然而,这种细菌在2岁以下患者的结肠正常菌群中是一种众所周知的污染物,因此,共识指南建议,除非有临床指征,否则不建议对这种感染进行常规检测。我们在此报告一例非常年幼的婴儿病例,该婴儿出现拒食、体重增加缓慢、腹胀等症状,影像学检查显示有结肠炎。内镜评估显示存在假膜性结肠炎,因此该患者接受了针对……的抗生素治疗并完全康复。这个病例表明,即使在非常年幼的患者中,在鉴别诊断时考虑假膜性结肠炎也很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5caf/7670329/15feef68750c/crg-0014-0522-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5caf/7670329/15feef68750c/crg-0014-0522-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5caf/7670329/15feef68750c/crg-0014-0522-g01.jpg

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Epidemiol Mikrobiol Imunol. 2019 Spring;68(2):59-64.
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Carriage and colonization of C. difficile in preterm neonates: A longitudinal prospective study.艰难梭菌在早产儿中的携带和定植:一项纵向前瞻性研究。
PLoS One. 2019 Feb 20;14(2):e0212568. doi: 10.1371/journal.pone.0212568. eCollection 2019.
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Clostridium difficile stool shedding in infants hospitalized in two neonatal intensive care units is lower than previous point prevalence estimates using molecular diagnostic methods.
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BMC Pediatr. 2018 Apr 13;18(1):137. doi: 10.1186/s12887-018-1113-z.
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Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).临床实践指南:成人和儿童艰难梭菌感染:美国传染病学会(IDSA)和美国医疗保健流行病学学会(SHEA) 2017 年更新。
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