Hu Juan, Chen Zichen, Zhang Yuzhong, Wei Xinyu, Zhao Huandi, Ren Pengyu, Han Peng, Cheng Ying, Shi Wendi, Zhang Qing
Department of Otorhinolaryngology Head and Neck Surgery,the Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China.
Department of Neurosurgery,the 2nd Affiliated Hospital of Xi'an Jiaotong University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Nov;34(11):993-998. doi: 10.13201/j.issn.2096-7993.2020.11.008.
This study aimed to assess the clinical practice value of ocular vestibular evoked myogenic potential(oVEMP) and cervical vestibular evoked myogenic potential(cVEMP) in monitoring the rehabilitation of vestibular function in patients with suddensen sorineural hearing loss(SSHL). Twenty-four patients with SSHL were retrospectively enrolled, showing no VEMP response on the affected side but exhibiting VEMP responses after therapies We analyzed the improvement and the restoration of hearing and the parameters of VEMP response. After treatment, seven patients showed VEMP recovery, including three cases with both oVEMP and cVEMP recovery, three cases with oVEMP recovery, and one case with cVEMP recovery. Between VEMP recoved group and VEMP unrecoved group, before treatment, no significant difference was found in the thresholds of pure-tone audiometry(PTA). However, after treatment, VEMP recoved group exhibited lower PTA thresholds and better PTA shift (<0.01). Multivariate analysis revealed that recovery of VEMP was the independent risk factor for the therapeutic effect of SSHL. The Combination of oVEMP and cVEMP is an objective tool for assessing vestibular otolithic end organ function during dynamic functional recovery in SSHL and the recovery of VEMP could predict the auditory improvement.
本研究旨在评估眼震前庭诱发肌源性电位(oVEMP)和颈震前庭诱发肌源性电位(cVEMP)在监测突发性聋(SSHL)患者前庭功能康复中的临床应用价值。回顾性纳入24例SSHL患者,其患侧无VEMP反应,但治疗后出现VEMP反应。我们分析了听力的改善和恢复情况以及VEMP反应参数。治疗后,7例患者出现VEMP恢复,其中3例oVEMP和cVEMP均恢复,3例oVEMP恢复,1例cVEMP恢复。VEMP恢复组和未恢复组在治疗前纯音听阈(PTA)阈值方面无显著差异。然而,治疗后,VEMP恢复组的PTA阈值更低,PTA变化更好(<0.01)。多因素分析显示,VEMP恢复是SSHL治疗效果的独立危险因素。oVEMP和cVEMP联合应用是评估SSHL动态功能恢复过程中前庭耳石终器功能的客观工具,VEMP的恢复可预测听力改善情况。