重度感音神经性听力损失儿童耳石功能的隐匿性丧失
The hidden loss of otolithic function in children with profound sensorineural hearing loss.
作者信息
Xu Xin-Da, Zhang Qing, Hu Juan, Zhang Yan, Chen Yan-Fei, Zhang Xiao-Tong, Xu Min
机构信息
Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Ear Institute of Xi'an Jiaotong University College of Medicine, Xi'an 710004, China; Department of Otology and Skull Base Surgery, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Hearing Science, Ministry of Health, Shanghai, China.
Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Ear Institute of Xi'an Jiaotong University College of Medicine, Xi'an 710004, China.
出版信息
Int J Pediatr Otorhinolaryngol. 2015 Jun;79(6):852-857. doi: 10.1016/j.ijporl.2015.03.017. Epub 2015 Mar 26.
OBJECTIVE
This study sought to define the profile of ocular and cervical vestibular-evoked myogenic potential (oVEMP and cVEMP) in children with profound sensorineural hearing loss (PSHL).
METHODS
The ACS-evoked oVEMPs and cVEMPs of 43 children with PSHL and 20 healthy children were investigated. The response rates, thresholds, amplitudes, P1 and N1 latencies, and interpeak latencies of VEMPs were analyzed. Each patient's medical record was summarized and classified.
RESULTS
The response rates of oVEMP and cVEMP in patients with PSHL were 58.1% and 61.9% respectively, which were significantly less than those in healthy children (both were 100%). In the children patients whose oVEMP or cVEMP could still be elicited, significant elevated thresholds and decreased amplitudes in VEMPs could be observed (p<0.05). However, in the summary of the medical records of all the 43 patients, it was showed that neither the patients and their parents nor the doctors noticed the balance problem and the loss of otolithic function.
CONCLUSIONS
The otolithic dysfunction, which could be easily ignored in children with PSHL, could be observed in VEMPs. In the process of diagnosis and treatment of PSHL, the vestibular function should obtain enough attention. VEMPs have special value in observation of the hidden loss of otolithic function, and could be an important vestibular assessment method for children with PSHL.
目的
本研究旨在明确重度感音神经性听力损失（PSHL）儿童的眼震前庭诱发肌源性电位（oVEMP）和颈震前庭诱发肌源性电位（cVEMP）特征。
方法
对43例PSHL儿童和20例健康儿童进行了气导刺激诱发的oVEMP和cVEMP检测。分析了VEMP的反应率、阈值、振幅、P1和N1潜伏期以及峰间潜伏期。总结并分类了每位患者的病历。
结果
PSHL患者的oVEMP和cVEMP反应率分别为58.1%和61.9%，显著低于健康儿童（均为100%）。在仍能引出oVEMP或cVEMP的儿童患者中，可观察到VEMP阈值显著升高和振幅降低（p<0.05）。然而，在所有43例患者的病历总结中，显示患者及其父母以及医生均未注意到平衡问题和耳石功能丧失。
结论
在VEMP中可观察到PSHL儿童易被忽视的耳石功能障碍。在PSHL的诊治过程中，前庭功能应得到足够重视。VEMP在观察耳石功能隐匿性丧失方面具有特殊价值，可为PSHL儿童提供一种重要的前庭评估方法。
Zotero 插件