Zhu Baolian, Yang Qin, Wang Juan
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Dec;34(12):1135-1136. doi: 10.13201/j.issn.2096-7993.2020.12.019.
The patient, a 70-year-old woman, presented with a mass in the right nasal cavity accompanied by recurrent nosebleeds for 3 months. Physical examination revealed a mass in the right nasal vestibule, with a diameter of about 1.5 cm. The surface of the mass was not smooth and nasal CT showed a mass in the right nasal vestibule, which could be surgically removed. Immunohistochemical results of the tumor showed CKpan（3+）, CK5/6（3+）, p40（3+）, p53（+）, CD10（-）, AR（-）, Bcl-2（-）, ki-67（+20%）. Pathological diagnosis was acantholytic dyskeratotic acanthoma. This disease is rare and easy to be misdiagnosed, so it is necessary to pay attention to identification.
患者为一名70岁女性，因右侧鼻腔肿物伴反复鼻出血3个月就诊。体格检查发现右侧鼻前庭有一肿物，直径约1.5厘米。肿物表面不光滑，鼻腔CT显示右侧鼻前庭有一肿物，可手术切除。肿瘤的免疫组化结果显示CKpan（3+）、CK5/6（3+）、p40（3+）、p53（+）、CD10（-）、AR（-）、Bcl-2（-）、ki-67（+20%）。病理诊断为棘层松解性角化不良性棘皮瘤。本病罕见且易误诊，故需注意鉴别。
