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内皮功能障碍的无创评估:预测重症 COVID-19 的新方法?

Non-invasive assessment of endothelial dysfunction: A novel method to predict severe COVID-19?

机构信息

Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 00800, Sri Lanka.

Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 00800, Sri Lanka.

出版信息

Med Hypotheses. 2020 Nov;144:110229. doi: 10.1016/j.mehy.2020.110229. Epub 2020 Sep 2.

Abstract

The COVID-19 pandemic caused by the SARS-CoV-2 virus has infected millions and overburdened the healthcare infrastructure globally. Recent studies show that the endothelial dysfunction caused by the virus contributes to its high morbidity and mortality. A parameter that can identify patients who will develop complications early will be valuable in patient management and reducing the burden on medical resources. An emerging technology is currently being tested to predict the cardiovascular risk via non-invasively measuring the endothelial dysfunction. This paper reviews how the assessment of endothelial dysfunction using this technology can be used as a potential parameter in the prognostication and management of COVID-19 patients.

摘要

由 SARS-CoV-2 病毒引起的 COVID-19 大流行已经感染了数百万人,并使全球的医疗基础设施不堪重负。最近的研究表明,病毒引起的内皮功能障碍导致了其高发病率和死亡率。能够早期识别出将发生并发症的患者的参数,对于患者管理和减轻医疗资源负担将具有重要价值。目前正在测试一种新兴技术,通过非侵入性测量内皮功能障碍来预测心血管风险。本文回顾了如何使用该技术评估内皮功能障碍,将其作为 COVID-19 患者预后和管理的潜在参数。

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引用本文的文献

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COVID-19, Renin-Angiotensin System and Endothelial Dysfunction.
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