Butler D L
Instr Course Lect. 1987;36:173-8.
Laboratory studies designed to simulate in vivo loading of a ligament graft and fixation method are affected by the age of the cadaveric donor, the types of tissue and fixation device employed, and the testing methods used. The use of older donors compromises the graft bone, underlying bone bed, and soft tissue. Staples, sutures, and screws all provide different fixation strengths depending on the tissue to be held. Cyclic testing of the graft better evaluates the performance of the composite during the activities of daily living, while high-speed failure tests indicate the replacement's ability to resist a traumatic injury. Several studies were examined in light of these factors. Each study had certain merits but also limitations. Further studies are required for careful evaluation of the cyclic response of cancellous screws of different sizes, barbed staples, and other methods of graft fixation. Only then can recommendations be made as to the best device to use for achieving the clinical goals of joint stability, adequate resistance to traumatic loads, and proper graft attachment healing.
旨在模拟韧带移植物体内负荷及固定方法的实验室研究，会受到尸体供体的年龄、所采用的组织类型和固定装置以及所使用的测试方法的影响。使用年长供体会损害移植物骨、下方的骨床和软组织。根据所要固定的组织不同，钉、缝线和螺钉都能提供不同的固定强度。对移植物进行循环测试能更好地评估复合材料在日常生活活动中的性能，而高速失效测试则表明替代品抵抗创伤性损伤的能力。鉴于这些因素，对多项研究进行了审查。每项研究都有一定的优点，但也存在局限性。需要进一步研究以仔细评估不同尺寸的松质骨螺钉、带倒刺钉以及其他移植物固定方法的循环反应。只有这样，才能就实现关节稳定性、对创伤负荷的充分抵抗力以及移植物附着愈合等临床目标的最佳装置提出建议。
