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纳米纤维素基材料在生物医学应用中的进展:综述。

Advances in Biomedical Application of Nanocellulose-Based Materials: A Review.

机构信息

Engineering Research Center of Forestry Biomass Materials and Bioenergy, Research Center of Biomass Clean Utilization, College of Materials Science and Technology, Beijing Forestry University, Beijing 100083,China.

出版信息

Curr Med Chem. 2021;28(40):8275-8295. doi: 10.2174/0929867328666201130124501.

Abstract

BACKGROUND

Recently, there has been increasing interest in nanomaterials processed using renewable and sustainable resources. Nanocellulose-based materials are of paramount value in the applications of biomedicine owing to their tailorable surface modification, favorable optical transparency, good hydrophilicity, excellent biocompatibility, and outstanding mechanical properties.

OBJECTIVE

In the review, the recent advancements of nanocellulose, including cellulose nanofibers (CNFs), cellulose nanocrystals (CNCs), and bacterial cellulose (BC), are summarized, which are promising for biomedical applications.

RESULTS

By discussing different forms (one-dimensional (1D), two-dimensional (2D), and three-dimensional (3D)), the superiority of the nanocellulose-based materials with different constructed structures will be clarified for various biomedical applications, such as biosensing, drug delivery, wound dressing, and tissue engineering.

CONCLUSION

The challenges and prospects for the future development of nanocellulose- based materials in biomedical applications are also discussed at the end of the review.

摘要

背景

最近,人们对使用可再生和可持续资源加工的纳米材料越来越感兴趣。基于纳米纤维素的材料由于其可定制的表面修饰、良好的光学透明度、良好的亲水性、优异的生物相容性和出色的机械性能,在生物医学应用中具有非常重要的价值。

目的

在综述中,总结了纳米纤维素,包括纤维素纳米纤维(CNFs)、纤维素纳米晶体(CNCs)和细菌纤维素(BC)的最新进展,这些材料在生物医学应用中具有广阔的前景。

结果

通过讨论不同的形式(一维(1D)、二维(2D)和三维(3D)),阐明了具有不同构建结构的纳米纤维素基材料在生物传感、药物输送、伤口敷料和组织工程等各种生物医学应用中的优势。

结论

在综述的最后,还讨论了纳米纤维素基材料在生物医学应用中的未来发展所面临的挑战和前景。

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