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银屑病患者中抑郁和焦虑的患病率及相关因素。

Prevalence and factors associated with depression and anxiety in patients with psoriasis.

机构信息

Nursing Department at FMB-UNESP, Botucatu, SP, Brazil.

Department of Dermatology at FMB-UNESP, Botucatu, SP, Brazil.

出版信息

J Clin Nurs. 2021 Feb;30(3-4):572-580. doi: 10.1111/jocn.15577. Epub 2020 Dec 27.

DOI:10.1111/jocn.15577
PMID:33258200
Abstract

OBJECTIVE

To identify the prevalence and factors associated with depression and anxiety in patients with psoriasis.

BACKGROUND

Psoriasis is a chronic, non-contagious, autoimmune inflammatory skin disease associated with psychological comorbidities.

DESIGN

A cross-sectional study conducted between March 2017-December 2018 in a dermatology infirmary and outpatient clinic of a public hospital in the inner State of São Paulo (Brazil).

METHODS

We used questionnaires with sociodemographic data and clinical history, the HADS (Hospital Anxiety and Depression Scale), DLQI-BRA (Dermatology Life Quality Index) and PASI (Psoriasis Area Severity Index). The correlations between variables were explored using multivariate techniques. STROBE checklist was applied as the reporting guideline for this study (File S1).

RESULTS

A total of 281 participants were included, of which the majority were female 146 (52%), with a mean age of 52.1 years (SD: 13.8), elementary school 154 (55%), married/cohabiting 209 (74%) and with low income 201 (72%). The median (p25-p75) time with the disease was 14 years (7-23). Regarding the quality of life, 31% of respondents reported being little affected by the disease. The prevalence of depression was 19% and that of anxiety was 36%. The multivariate analysis showed that the variables that influenced the anxiety and depression scores were as follows: DLQI-BRA, income, female sex, illness length and age. For the multiple correspondence analysis, the highest levels of anxiety and depression referred to women, middle age, lower income and low PASI.

CONCLUSION

The prevalence of anxiety and depression symptoms was low. Female sex, income, age, illness length and quality of life were associated with anxiety and depression scores in patients with psoriasis.

RELEVANCE TO CLINICAL PRACTICE

Due to the scarcity of studies in the field of nursing with psoriasis patients, we believe these findings contribute to the reorganisation of the care provided, allowing nurses to timely identify mood disorders such as anxiety and depression and adopt the necessary measures to a service and/or specialised referral.

摘要

目的

确定银屑病患者中抑郁和焦虑的患病率及其相关因素。

背景

银屑病是一种慢性、非传染性、自身免疫性炎症性皮肤病,与心理合并症有关。

设计

这是一项于 2017 年 3 月至 2018 年 12 月在巴西内地一家公立医院皮肤科医务室和门诊诊所进行的横断面研究。

方法

我们使用了带有社会人口统计学数据和临床病史的问卷、HADS(医院焦虑和抑郁量表)、DLQI-BRA(皮肤病生活质量指数)和 PASI(银屑病面积严重程度指数)。使用多变量技术探索变量之间的相关性。STROBE 清单被用作本研究的报告指南(文件 S1)。

结果

共纳入 281 名参与者,其中大多数为女性 146 名(52%),平均年龄为 52.1 岁(标准差:13.8),小学文化程度 154 名(55%),已婚/同居 209 名(74%)和低收入 201 名(72%)。中位数(25%分位数-75%分位数)患病时间为 14 年(7-23 年)。关于生活质量,31%的受访者表示受疾病影响较小。抑郁的患病率为 19%,焦虑的患病率为 36%。多变量分析表明,影响焦虑和抑郁评分的变量有:DLQI-BRA、收入、女性、疾病持续时间和年龄。对于多重对应分析,焦虑和抑郁程度最高的是女性、中年、低收入和低 PASI。

结论

焦虑和抑郁症状的患病率较低。女性、收入、年龄、疾病持续时间和生活质量与银屑病患者的焦虑和抑郁评分相关。

临床意义

由于护理领域针对银屑病患者的研究稀缺,我们认为这些发现有助于重新组织提供的护理,使护士能够及时识别焦虑和抑郁等情绪障碍,并采取必要措施为患者提供服务和/或转介到专门机构。

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