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建立一个全国性的 2019 冠状病毒病韩国影像队列。

Establishment of a Nationwide Korean Imaging Cohort of Coronavirus Disease 2019.

机构信息

Department of Radiology, Seoul National University Hospital, Seoul National College of Medicine, Seoul, Korea.

Department of Radiology, Kangbuk Samsung Hospital, Seoul, Korea.

出版信息

J Korean Med Sci. 2020 Nov 30;35(46):e413. doi: 10.3346/jkms.2020.35.e413.

DOI:10.3346/jkms.2020.35.e413
PMID:33258333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7707929/
Abstract

BACKGROUND

The Korean Society of Thoracic Radiology (KSTR) recently constructed a nation-wide coronavirus disease 2019 (COVID-19) database and imaging repository, referred to the Korean imaging cohort of COVID-19 (KICC-19) based on the collaborative efforts of its members. The purpose of this study was to provide a summary of the clinico-epidemiological data and imaging data of the KICC-19.

METHODS

The KSTR members at 17 COVID-19 referral centers retrospectively collected imaging data and clinical information of consecutive patients with reverse transcription polymerase chain reaction-proven COVID-19 in respiratory specimens from February 2020 through May 2020 who underwent diagnostic chest computed tomography (CT) or radiograph in each participating hospital.

RESULTS

The cohort consisted of 239 men and 283 women (mean age, 52.3 years; age range, 11-97 years). Of the 522 subjects, 201 (38.5%) had an underlying disease. The most common symptoms were fever (n = 292) and cough (n = 245). The 151 patients (28.9%) had lymphocytopenia, 86 had (16.5%) thrombocytopenia, and 227 patients (43.5%) had an elevated CRP at admission. The 121 (23.4%) needed nasal oxygen therapy or mechanical ventilation (n = 38; 7.3%), and 49 patients (9.4%) were admitted to an intensive care unit. Although most patients had cured, 21 patients (4.0%) died. The 465 (89.1%) subjects underwent a low to standard-dose chest CT scan at least once during hospitalization, resulting in a total of 658 CT scans. The 497 subjects (95.2%) underwent chest radiography at least once during hospitalization, which resulted in a total of 1,475 chest radiographs.

CONCLUSION

The KICC-19 was successfully established and comprised of 658 CT scans and 1,475 chest radiographs of 522 hospitalized Korean COVID-19 patients. The KICC-19 will provide a more comprehensive understanding of the clinical, epidemiological, and radiologic characteristics of patients with COVID-19.

摘要

背景

韩国胸放射学会(KSTR)最近构建了一个全国性的 2019 年冠状病毒病(COVID-19)数据库和影像学资料库,该资料库基于其成员的合作,被称为韩国 COVID-19 影像学队列(KICC-19)。本研究的目的是总结 KICC-19 的临床流行病学数据和影像学数据。

方法

2020 年 2 月至 5 月期间,17 家 COVID-19 转诊中心的 KSTR 成员回顾性收集了经呼吸道标本逆转录聚合酶链反应证实的 COVID-19 连续患者的影像学数据和临床信息,这些患者在每个参与医院均接受了诊断性胸部计算机断层扫描(CT)或 X 线摄影。

结果

该队列包括 239 名男性和 283 名女性(平均年龄 52.3 岁;年龄范围 11-97 岁)。522 名受试者中 201 名(38.5%)有基础疾病。最常见的症状是发热(n=292)和咳嗽(n=245)。151 例患者(28.9%)出现淋巴细胞减少症,86 例(16.5%)出现血小板减少症,227 例(43.5%)入院时 C 反应蛋白升高。121 例(23.4%)需要鼻氧疗或机械通气(n=38;7.3%),49 例(9.4%)患者收入重症监护病房。尽管大多数患者已治愈,但仍有 21 例(4.0%)患者死亡。465 例(89.1%)患者在住院期间至少接受过一次低剂量或标准剂量胸部 CT 扫描,共进行了 658 次 CT 扫描。497 例(95.2%)患者在住院期间至少接受过一次胸部 X 线摄影,共进行了 1475 次胸部 X 线摄影。

结论

KICC-19 成功建立,包括 522 例韩国 COVID-19 住院患者的 658 次 CT 扫描和 1475 次胸部 X 线摄影。KICC-19 将提供对 COVID-19 患者临床、流行病学和影像学特征的更全面了解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3792/7707929/d526c3dee7b6/jkms-35-e413-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3792/7707929/618d224849f2/jkms-35-e413-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3792/7707929/d526c3dee7b6/jkms-35-e413-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3792/7707929/618d224849f2/jkms-35-e413-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3792/7707929/d526c3dee7b6/jkms-35-e413-g002.jpg

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