Department of Epidemiology and Global Health, Faculty of Medicine, Umeå University, Umeå, 90185, Sweden.
J Travel Med. 2020 Dec 23;27(8). doi: 10.1093/jtm/taaa222.
INTRODUCTION: GeoSentinel is a global surveillance network of travel medicine providers seeing ill-returned travellers. Much of our knowledge on health problems and infectious encountered by international travellers has evolved as a result of GeoSentinel surveillance, providing geographic and temporal trends in morbidity among travellers while contributing to improved pre-travel advice. We set out to synthesize epidemiological information, clinical manifestations and time trends for dengue, chikungunya and Zika in travellers as captured by GeoSentinel. METHODS: We conducted a systematic literature search in PubMed on international travellers who presented with dengue, chikungunya or Zika virus infections to GeoSentinel sites around the world from 1995 until 2020. RESULTS: Of 107 GeoSentinel publications, 42 articles were related to dengue, chikungunya and/or Zika. The final analyses and synthesis of and results presented here are based on the findings from 27 original articles covering the three arboviral diseases. CONCLUSIONS: Dengue is the most frequent arboviral disease encountered in travellers presenting to GeoSentinel sites, with increasing trends over the past two decades. In Southeast Asia, annual proportionate morbidity increased from 50 dengue cases per 1000 ill returned travellers in non-epidemic years to an average of 159 cases per 1000 travellers during epidemic years. The highest number of travellers with chikungunya virus infections was reported during the chikungunya outbreak in the Americas and the Caribbean in the years 2013-16. Zika was first reported by GeoSentinel already in 2012, but notifications peaked in the years 2016-17 reflecting the public health emergency in the Americas at the time.
简介:GeoSentinel 是一个旅行医学提供者的全球监测网络,专门为返回的旅行者提供医疗服务。我们对国际旅行者所遇到的健康问题和传染病的了解在很大程度上是通过 GeoSentinel 监测发展而来的,它提供了旅行者发病率的地理和时间趋势,同时有助于改进旅行前的建议。我们旨在综合旅行者中登革热、基孔肯雅热和寨卡病毒的流行病学信息、临床表现和时间趋势。
方法:我们在 PubMed 上进行了系统的文献检索,检索了 1995 年至 2020 年期间在全球 GeoSentinel 站点就诊的患有登革热、基孔肯雅热或寨卡病毒感染的国际旅行者。
结果:在 107 篇 GeoSentinel 出版物中,有 42 篇文章与登革热、基孔肯雅热和/或寨卡病毒有关。这里最终分析和综合以及呈现的结果是基于 27 篇涵盖三种虫媒病毒疾病的原始文章的发现。
结论:登革热是旅行者在 GeoSentinel 站点就诊时最常见的虫媒病毒病,在过去二十年中呈上升趋势。在东南亚,非流行年份每千名返回旅行者中登革热的发病比例从 50 例增加到流行年份的平均 159 例。在美洲和加勒比地区的基孔肯雅热疫情期间,报告的旅行者感染基孔肯雅热病毒的人数最多。GeoSentinel 于 2012 年首次报告了寨卡病毒,但在当时美洲的公共卫生紧急情况期间,2016-17 年的通报数量达到了高峰。
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