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利用疾病特异性工具增强多发性硬化症的认知康复。

Enhancing cognitive rehabilitation in multiple sclerosis with a disease-specific tool.

机构信息

Department of Computer Science and Engineering, University of Bologna, Bologna, Italy.

Faculty of Computer Science, Free University of Bozen-Bolzano, Bolzano, Italy.

出版信息

Disabil Rehabil Assist Technol. 2023 Apr;18(3):313-326. doi: 10.1080/17483107.2020.1849432. Epub 2020 Dec 1.

Abstract

PURPOSE

Computerised rehabilitation programs can be used to address cognitive deficits typically caused by multiple sclerosis (MS). However, there are still doubts on their effectiveness, due to mixed results obtained in clinical trials. The objective of this paper is to improve cognitive rehabilitation (CR) practices in MS, by presenting and assessing a MS-specific cognitive rehabilitation software.

METHODS

We conducted a detailed analysis of how CR is carried out in practice in MS rehabilitation centres. From the analysis, we elicited a reference CR process, and identified the essential features a software supporting the process should have. We designed and implemented MS-rehab, a novel MS-specific computerised rehabilitation system having the identified features. We experimented MS-rehab in a pilot study involving eight MS patients. To highlight the improvement with respect to the state of the art, we compared MS-rehab with available professional tools selected using well defined criteria.

RESULTS

This paper has three main contributions: (1) the identification of a set of essential features a computerised tool for CR in MS should provide; (2) MS-rehab, a novel CR system designed for MS therapists and patients, which embodies innovative MS specific features; (3) the assessment of MS-rehab efficacy in a pilot study with MS patients.

CONCLUSIONS

The availability of a MS-specific CR system like MS-rehab fosters the design of more rigorous clinical studies on the effectiveness of computerised rehabilitation in MS. MS-rehab demonstrated its potential and innovativeness as a tool for cognitive rehabilitation in MS.IMPLICATIONS FOR REHABILITATIONComputerized tools for cognitive rehabilitation (CR) in multiple sclerosis (MS) can be improved by a set of MS-specific features.The availability of advanced home-based cognitive rehabilitation mechanisms is fundamental for supporting standardized cognitive rehabilitation protocols in MS.A MS-specific CR system has given promising results in a pilot study involving MS patients.Hardly do state-of-the-art professional tools include all the required MS specific features.

摘要

目的

计算机康复程序可用于解决多发性硬化症(MS)通常引起的认知缺陷。然而,由于临床试验结果不一,其有效性仍存在疑问。本文的目的是通过提出和评估一种特定于多发性硬化症的认知康复软件,改善多发性硬化症康复中心的认知康复实践。

方法

我们对多发性硬化症康复中心的认知康复实践进行了详细分析。通过分析,我们得出了一个参考认知康复过程,并确定了支持该过程的软件应具备的基本特征。我们设计并实现了 MS-rehab,这是一种新颖的特定于多发性硬化症的计算机化康复系统,具有所确定的特征。我们在一项涉及 8 名多发性硬化症患者的试点研究中对 MS-rehab 进行了实验。为了突出与现有技术相比的改进,我们使用明确定义的标准选择了可用的专业工具,并将 MS-rehab 与这些工具进行了比较。

结果

本文有三个主要贡献:(1)确定了一套多发性硬化症患者认知康复计算机工具应具备的基本特征;(2)MS-rehab,一种为多发性硬化症治疗师和患者设计的新型认知康复系统,体现了创新的多发性硬化症特定功能;(3)在多发性硬化症患者的试点研究中评估 MS-rehab 的疗效。

结论

像 MS-rehab 这样的特定于多发性硬化症的认知康复系统的可用性促进了计算机康复在多发性硬化症中的有效性的更严格的临床研究的设计。MS-rehab 作为多发性硬化症认知康复的工具,表现出了其潜力和创新性。

对康复的启示

多发性硬化症认知康复的计算机工具可以通过一组多发性硬化症特有的功能得到改进。先进的家用认知康复机制的可用性对于支持多发性硬化症的标准化认知康复协议至关重要。一种特定于多发性硬化症的认知康复系统在一项涉及多发性硬化症患者的试点研究中取得了有希望的结果。现有的专业工具几乎没有包含所有必需的多发性硬化症特定功能。

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