Haverkorn M J
Laboratory for Medical Microbiology, Endhoven, The Netherlands.
Pharm Weekbl Sci. 1987 Dec 11;9 Suppl:S64-7. doi: 10.1007/BF02075264.
Thirty one patients were treated with oral ciprofloxacin for bronchitis with Pseudomonas aeruginosa. Twenty eight patients had permanent and 14 transient risk factors. Nine patients had a hospital infection with Pseudomonas aeruginosa. Sixteen patients were cured, complete or partial, but Pseudomonas aeruginosa persisted or recurred in 19 patients. Patients with hospital infection did better than other patients. There was a significant decrease in in vitro susceptibility of persisting strains of Pseudomonas aeruginosa to ciprofloxacin and a tendency of recovery of susceptibility for the drug after treatment.
31例患有铜绿假单胞菌支气管炎的患者接受了口服环丙沙星治疗。28例患者有永久性危险因素，14例有暂时性危险因素。9例患者发生了铜绿假单胞菌医院感染。16例患者治愈，包括完全治愈或部分治愈，但19例患者的铜绿假单胞菌持续存在或复发。发生医院感染的患者比其他患者情况更好。持续存在的铜绿假单胞菌菌株对环丙沙星的体外敏感性显著降低，且治疗后该药物的敏感性有恢复趋势。
