Șurlin Petra, Nicolae Flavia Mirela, Șurlin Valeriu Marin, Pătrașcu Ștefan, Ungureanu Bogdan Silviu, Didilescu Andreea Cristiana, Gheonea Dan Ionuț
Department of Periodontology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Department 1st of Surgery, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
J Clin Med. 2020 Nov 29;9(12):3885. doi: 10.3390/jcm9123885.
Periodontal disease affects the supporting tissues of the teeth, being a chronic inflammatory disease caused by specific microorganisms from subgingival biofilm. is a Gram-negative anaerobic bacterium that acts as a periodontal pathogen, being an important factor in linking Gram-positive and Gram-negative bacteria in the periodontal biofilm, but its involvement in systemic diseases has also been found. Several studies regarding the implication of in gastro-enterological cancers have been conducted. The present review aims to update and systematize the latest information about in order to evaluate the possibility of an association between periodontal disease and the evolution of gastroenterological cancers through the action of , highlighting gastric cancer. This would motivate future research on the negative influence of periodontal pathology on the evolution of gastric cancer in patients suffering from both pathologies.
牙周病会影响牙齿的支持组织，是一种由龈下生物膜中的特定微生物引起的慢性炎症性疾病。 是一种革兰氏阴性厌氧菌，作为牙周病原体发挥作用，是牙周生物膜中连接革兰氏阳性菌和革兰氏阴性菌的重要因素，但也发现其与全身性疾病有关。已经开展了多项关于 在胃肠癌中的影响的研究。本综述旨在更新和系统化关于 的最新信息，以便通过 的作用评估牙周病与胃肠癌进展之间关联的可能性，重点是胃癌。这将推动未来针对牙周病理对同时患有这两种疾病的患者胃癌进展的负面影响的研究。
