Vander Haar Emilie L, So Jeewon, Gyamfi-Bannerman Cynthia, Han Yiping W
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY, USA.
Institute of Human Nutrition, College of Physicians & Surgeons, Columbia University Medical Center, New York, NY, USA.
Anaerobe. 2018 Apr;50:55-59. doi: 10.1016/j.anaerobe.2018.01.008. Epub 2018 Feb 2.
Fusobacterium nucleatum is a Gram-negative anaerobic oral commensal associated with periodontal disease. F. nucleatum has been implicated in a wide spectrum of systemic diseases, including oral, gastro-intestinal, rheumatologic, and vascular pathologies. As pregnancy risk has been linked to periodontal disease, there has also been significant research into the effects of periodontal disease on adverse pregnancy outcomes. This article reviews the epidemiological and mechanistic evidence of the role of F. nucleatum in adverse pregnancy outcomes.
具核梭杆菌是一种与牙周疾病相关的革兰氏阴性厌氧口腔共生菌。具核梭杆菌与多种全身性疾病有关，包括口腔、胃肠道、风湿性和血管疾病。由于妊娠风险与牙周疾病有关，因此也对牙周疾病对不良妊娠结局的影响进行了大量研究。本文综述了具核梭杆菌在不良妊娠结局中作用的流行病学和机制证据。
