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使用针对弹性纤维微原纤维蛋白的特异性抗血清进行免疫荧光研究。在弹性和非弹性结缔组织中的定位。

Immunofluorescence studies with a specific antiserum to the microfibrillar protein of elastic fibres. Location in elastic and non-elastic connective tissues.

作者信息

Kewley M A, Steven F S, Williams G

出版信息

Immunology. 1977 Sep;33(3):381-6.

PMID:332620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445654/
Abstract

The microfibrillar protein (MFP) of foetal bovine ligamentum nuchae elastic fibres was prepared and used to produce a monospecific antiserum. Indirect immunofluorescence studies employing the specific antiserum demonstrated its selectivity for MFP associated with elastic fibres. The antiserum was demonstrated to react with vascular elastic tissue, perivascular connective tissue and reticular basement membranes in a variety of tissues. This evidence suggests that the MFP (or an immunologically related protein) is not confined to elastic fibres but is widely distributed in connective tissue being associated with both elastin and collagen fibres.

摘要

制备了胎牛项韧带弹性纤维的微原纤维蛋白(MFP),并用于制备单特异性抗血清。使用该特异性抗血清进行的间接免疫荧光研究证明了其对与弹性纤维相关的MFP的选择性。已证明该抗血清可与多种组织中的血管弹性组织、血管周围结缔组织和网状基底膜发生反应。这一证据表明,MFP(或一种免疫相关蛋白)不仅局限于弹性纤维,还广泛分布于与弹性蛋白和胶原纤维相关的结缔组织中。

相似文献

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Immunofluorescence studies with a specific antiserum to the microfibrillar protein of elastic fibres. Location in elastic and non-elastic connective tissues.使用针对弹性纤维微原纤维蛋白的特异性抗血清进行免疫荧光研究。在弹性和非弹性结缔组织中的定位。
Immunology. 1977 Sep;33(3):381-6.
2
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The tissue distribution of microfibrils reacting with a monospecific antibody to MAGP, the major glycoprotein antigen of elastin-associated microfibrils.与弹性蛋白相关微原纤维的主要糖蛋白抗原MAGP的单特异性抗体发生反应的微原纤维的组织分布。
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引用本文的文献

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Ultrastructure of Reichert's membrane, a multilayered basement membrane in the parietal wall of the rat yolk sac.大鼠卵黄囊壁层中多层基底膜——赖歇特膜的超微结构
J Cell Biol. 1983 Nov;97(5 Pt 1):1524-37. doi: 10.1083/jcb.97.5.1524.

本文引用的文献

1
A Simple Method for the Silver Impregnation of Reticulum.一种用于网状纤维镀银的简单方法。
Am J Pathol. 1936 Jul;12(4):545-552.1.
2
Microfibrils: fine filamentous components of the tissue space.微原纤维:组织间隙中的细丝状成分。
Anat Rec. 1962 Feb;142:131-7. doi: 10.1002/ar.1091420205.
3
An electron microscope study of the aorta in young and in aging mice.对年轻和衰老小鼠主动脉的电子显微镜研究。
J Ultrastruct Res. 1961 Mar;5:1-27. doi: 10.1016/s0022-5320(61)80002-6.
4
Glomerular permeability. I. Ferritin transfer across the normal glomerular capillary wall.肾小球通透性。I. 铁蛋白穿过正常肾小球毛细血管壁的转运。
J Exp Med. 1961 Jan 1;113(1):47-66. doi: 10.1084/jem.113.1.47.
5
The fine structure of connective tissue in the tunica propria of bronchioles.细支气管固有层结缔组织的精细结构。
J Ultrastruct Res. 1958 Nov;2(1):96-121. doi: 10.1016/s0022-5320(58)90049-2.
6
Presence of carbohydrates with free 1,2-glycol groups in sites stained by the periodic acid-Schiff technique.在经高碘酸-希夫技术染色的部位存在带有游离1,2-二醇基团的碳水化合物。
J Histochem Cytochem. 1957 Sep;5(5):445-58. doi: 10.1177/5.5.445.
7
Electron microscopy of collagen and elastin in lamina propria of the tracheal muscosa of rat.大鼠气管黏膜固有层中胶原蛋白和弹性蛋白的电子显微镜观察
Exp Cell Res. 1955 Oct;9(2):371-5. doi: 10.1016/0014-4827(55)90116-6.
8
The elastic fiber. I. The separation and partial characterization of its macromolecular components.弹性纤维。I. 其大分子成分的分离与部分特性分析。
J Cell Biol. 1969 Feb;40(2):366-81. doi: 10.1083/jcb.40.2.366.
9
Specific antibodies produced against antigens of agar-gel precipitates.针对琼脂凝胶沉淀抗原产生的特异性抗体。
Immunology. 1967 Dec;13(6):547-54.
10
Isolation of a non-collagenous reticulin component and its primary characterization.一种非胶原网状蛋白成分的分离及其初步表征。
Br J Exp Pathol. 1973 Aug;54(4):449-56.