Kumar Srinivas Ananth, Singh Harmandeep, Kaman Lileswar, Nada Ritambhra, Mittal Bhagwant Rai
Department of Nuclear Medicine and PET/CT, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Nucl Med Mol Imaging. 2024 May;58(3):140-146. doi: 10.1007/s13139-024-00846-5. Epub 2024 Feb 14.
Fibromatoses are a heterogeneous group of benign proliferating fibroblasts and myofibroblasts which have a high predilection for recurrence and local invasion, especially deep fibromatoses or desmoid fibromatosis. F-FDG PET/CT, the workhorse of oncological imaging in nuclear medicine, can be employed to figure out the nature and aggressiveness of the lesions and various sites of involvement and to monitor treatment response to systemic therapies like tyrosine kinase inhibitors in case of deep or desmoid fibromatoses which is shown in the current research work.
纤维瘤病是一组由良性增殖性成纤维细胞和平滑肌成纤维细胞组成的异质性疾病,具有很高的复发和局部侵袭倾向,尤其是深部纤维瘤病或韧带样型纤维瘤病。F-FDG PET/CT是核医学肿瘤成像的主要手段,可用于明确病变的性质、侵袭性、受累的各个部位,并监测深部或韧带样型纤维瘤病对酪氨酸激酶抑制剂等全身治疗的反应,本研究工作对此进行了展示。