Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.
Medical College of Georgia at Augusta University, Augusta, Georgia.
Ocul Immunol Inflamm. 2023 Oct;31(8):1635-1639. doi: 10.1080/09273948.2022.2091616. Epub 2022 Jul 25.
To characterize fluorescein angiography (FA) features in pediatric uveitis.
A retrospective cross-sectional study of pediatric uveitis patients in Atlanta, GA, who had FA imaging between May 2009 and August 2020.
A total of 137 eyes of 88 patients were evaluated. The mean FA score in anterior uveitis was lower than that in other categories (p = .0093). The mean FA score in the clinically active group was higher than that in the clinically inactive group (p = .0057). The mean FA score in eyes 20/40 or better was lower than that in other categories (p = .0292). Worse visual acuity was associated with retinal vascular staining/leakage, retinal staining/pooling, and neovascularization elsewhere. Non-infectious uveitis more often demonstrated optic disc hyperfluorescence, retinal vascular staining/leakage, capillary leakage, and pinpoint leaks, while infectious uveitis more often demonstrated retinal staining/pooling.
A standardized quantitative FA scoring system can be useful in the characterization of uveitis in pediatric patients.
描述儿童葡萄膜炎的荧光素血管造影（FA）特征。
这是一项在佐治亚州亚特兰大进行的回顾性病例系列研究，纳入了 2009 年 5 月至 2020 年 8 月间进行 FA 成像的儿童葡萄膜炎患者。
共评估了 88 例患者的 137 只眼。前葡萄膜炎的平均 FA 评分低于其他类别（p=0.0093）。临床活动组的平均 FA 评分高于临床非活动组（p=0.0057）。20/40 或更好视力的眼的平均 FA 评分低于其他类别（p=0.0292）。更差的视力与视网膜血管染色/渗漏、视网膜染色/积聚以及其他部位的新生血管形成有关。非感染性葡萄膜炎更常表现为视盘强荧光、视网膜血管染色/渗漏、毛细血管渗漏和针尖样渗漏，而感染性葡萄膜炎更常表现为视网膜染色/积聚。
标准化的定量 FA 评分系统可用于描述儿童葡萄膜炎的特征。
