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[神经梅毒的大剂量静脉青霉素治疗。III. 脑脊液和血清中IgM类抗梅毒螺旋体抗体的评估]

[High-dose intravenous penicillin therapy in neurosyphilis. III. Evaluation of antitreponemal antibodies of the IgM class in cerebrospinal fluid and serum].

作者信息

Nitrini R, Ueda M, Vaz A J, Spina-França A

机构信息

Clínica Neurológica do Hospital das Clínicas da Faculdade de Medicina da Univrersidade de São Paulo.

出版信息

Arq Neuropsiquiatr. 1987 Sep;45(3):242-7. doi: 10.1590/s0004-282x1987000300004.

Abstract

IgM antibodies against Treponema pallidum were investigated in the serum and in the CSF of 9 patients with symptomatic neurosyphilis, before the treatment and in several occasions after the treatment. Tests used were the FTA-Abs test, the IgM-solid phase hemadsorption test and an IgM-Elisa test. Titers of reactions decreased after treatment but they were still reactive in the blood and in the CSF during the second year after the treatment.

摘要

对9例有症状神经梅毒患者在治疗前及治疗后的几个阶段,检测其血清和脑脊液中抗梅毒螺旋体IgM抗体。采用的检测方法有荧光密螺旋体抗体吸收试验(FTA - Abs试验)、IgM固相血吸附试验和IgM酶联免疫吸附试验(IgM - Elisa试验)。治疗后反应滴度下降,但在治疗后的第二年,血液和脑脊液中仍呈阳性反应。

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