Zommiti Mohamed, Feuilloley Marc G J, Connil Nathalie
Unité de Protéomique Fonctionnelle et Potentiel Nutraceutique de la Biodiversité de Tunisie, Institut Supérieur des Sciences Biologiques Appliquées de Tunis, Université Tunis El-Manar, Tunis 1006, Tunisia.
Laboratoire de Microbiologie Signaux et Microenvironnement (LMSM) EA 4312, Université de Rouen Normandie, Normandie Université, F-27000 Evreux, France.
Microorganisms. 2020 Nov 30;8(12):1907. doi: 10.3390/microorganisms8121907.
Lactic acid bacteria (LAB) are known for their biotechnological potential. Moreover, LAB are distinguished by amazing criteria: Adjusting the intestinal environment, inhibiting pathogenic microbes in the gastrointestinal tract, ability to reduce pathogen adhesion activity, improving the balance of the microbiota inside the intestine, capabilities of regulating intestinal mucosal immunity, and maintaining intestinal barrier function. The escalating number of research and studies about beneficial microorganisms and their impact on promoting health has attracted a big interest in the last decades. Since antiquity, various based fermented products of different kinds have been utilized as potential probiotic products. Nevertheless, the current upsurge in consumers' interest in bioalternatives has opened new horizons for the probiotic field in terms of research and development. The present review aims at shedding light on the world of probiotics, a continuous story of astonishing success in various fields, in particular, the biomedical sector and pharmaceutical industry, as well as to display the importance of probiotics and their therapeutic potential in purpose to compete for sturdy pathogens and to struggle against diseases and acute infections. Shadows and future trends of probiotics use are also discussed.
乳酸菌(LAB)以其生物技术潜力而闻名。此外,乳酸菌具有令人惊叹的特性:调节肠道环境、抑制胃肠道中的致病微生物、降低病原体黏附活性的能力、改善肠道内微生物群的平衡、调节肠道黏膜免疫的能力以及维持肠道屏障功能。在过去几十年中,关于有益微生物及其对促进健康影响的研究数量不断增加,引起了广泛关注。自古以来,各种不同类型的发酵产品就被用作潜在的益生菌产品。然而,当前消费者对生物替代品兴趣的激增为益生菌领域在研发方面开辟了新的前景。本综述旨在阐明益生菌的世界,这是一个在各个领域,特别是生物医学领域和制药行业不断取得惊人成功的故事,同时展示益生菌的重要性及其治疗潜力,以对抗强大的病原体并抵御疾病和急性感染。还讨论了益生菌使用的现状和未来趋势。