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益生菌通过改变单胃动物的免疫状态对肠道健康产生的影响。

The impact of probiotics on gut health via alternation of immune status of monogastric animals.

作者信息

Ding Sujuan, Yan Wenxin, Ma Yong, Fang Jun

机构信息

College of Bioscience and Biotechnology, Hunan Agricultural University, Hunan Provincial Engineering Research Center of Applied Microbial Resources Development for Livestock and Poultry, Changsha, 410128, China.

出版信息

Anim Nutr. 2021 Mar;7(1):24-30. doi: 10.1016/j.aninu.2020.11.004. Epub 2020 Dec 26.

Abstract

The intestinal immune system is affected by various factors during its development, such as maternal antibodies, host genes, intestinal microbial composition and activity, and various stresses (such as weaning stress). Intestinal microbes may have an important impact on the development of the host immune system. Appropriate interventions such as probiotics may have a positive effect on intestinal immunity by regulating the composition and activity of intestinal microbes. Moreover, probiotics participate in the regulation of host health in many ways; for instance, by improving digestion and the absorption of nutrients, immune response, increasing the content of intestinal-beneficial microorganisms, and inhibiting intestinal-pathogenic bacteria, and they participate in regulating intestinal diseases in various ways. Probiotics are widely used as additives in livestock and the poultry industry and bring health benefits to hosts by improving intestinal microbes and growth performance, which provides more choices for promoting strong and efficient productivity.

摘要

肠道免疫系统在其发育过程中受到多种因素的影响,如母体抗体、宿主基因、肠道微生物组成与活性以及各种应激(如断奶应激)。肠道微生物可能对宿主免疫系统的发育产生重要影响。诸如益生菌等适当干预措施可能通过调节肠道微生物的组成与活性对肠道免疫产生积极作用。此外,益生菌通过多种方式参与宿主健康的调节;例如,通过改善营养物质的消化与吸收、免疫反应、增加肠道有益微生物的含量以及抑制肠道病原菌,并且它们以多种方式参与肠道疾病的调节。益生菌作为添加剂在畜牧和家禽业中被广泛使用,并通过改善肠道微生物和生长性能给宿主带来健康益处,这为促进强大而高效的生产力提供了更多选择。

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