Trybek Paulina, Nowakowski Michal, Salowka Jerzy, Spiechowicz Jakub, Machura Lukasz
Division of Computational Physics and Electronics, Institute of Physics, Silesian Centre for Education and Interdisciplinary Research, University of Silesia in Katowice, 40007 Katowice, Poland.
Department of General Surgery and Multiorgan Trauma, Jagiellonian University Medical College, 30048 Krakow, Poland.
Entropy (Basel). 2018 Nov 9;20(11):863. doi: 10.3390/e20110863.
Information theory provides a spectrum of nonlinear methods capable of grasping an internal structure of a signal together with an insight into its complex nature. In this work, we discuss the usefulness of the selected entropy techniques for a description of the information carried by the surface electromyography signals during colorectal cancer treatment. The electrical activity of the external anal sphincter can serve as a potential source of knowledge of the actual state of the patient who underwent a common surgery for rectal cancer in the form of anterior or lower anterior resection. The calculation of Sample entropy parameters has been extended to multiple time scales in terms of the Multiscale Sample Entropy. The specific values of the entropy measures and their dependence on the time scales were analyzed with regard to the time elapsed since the operation, the type of surgical treatment and also the different depths of the rectum canal. The Mann-Whitney U test and Anova Friedman statistics indicate the statistically significant differences among all of stages of treatment and for all consecutive depths of rectum area for the estimated Sample Entropy. The further analysis at the multiple time scales signify the substantial differences among compared stages of treatment in the group of patients who underwent the lower anterior resection.
信息论提供了一系列非线性方法，这些方法能够把握信号的内部结构，并深入洞察其复杂本质。在这项工作中，我们讨论了所选熵技术对于描述结直肠癌治疗期间表面肌电信号所携带信息的有用性。肛门外括约肌的电活动可作为了解接受直肠癌常见手术（如前切除术或低位前切除术）患者实际状态的潜在知识来源。样本熵参数的计算已根据多尺度样本熵扩展到多个时间尺度。针对术后经过的时间、手术治疗类型以及直肠管不同深度，分析了熵度量的具体值及其对时间尺度的依赖性。曼 - 惠特尼U检验和方差分析弗里德曼统计表明，对于估计的样本熵，治疗的所有阶段以及直肠区域所有连续深度之间存在统计学上的显著差异。在多个时间尺度上的进一步分析表明，接受低位前切除术的患者组中，所比较的治疗阶段之间存在实质性差异。
