Department of General Surgery, Xiangya Hospital Central South University, Changsha, Hunan Province, China.
Hunan Key Laboratory of Precise Diagnosis and Treatment of Gastrointestinal Tumor, Xiangya Hospital Central South University, Changsha, Hunan Province, China.
Expert Rev Gastroenterol Hepatol. 2021 Apr;15(4):447-458. doi: 10.1080/17474124.2021.1842192. Epub 2020 Dec 3.
Magnetic endoscopic imaging (MEI) was regarded as an adjuvant device to improve procedural efficacy and patients' comfort during colonoscopy.
Several electronic databases were searched to identify eligible studies. Based on the heterogeneity of included studies, random-effects or fixed-effects models were used to calculate pooled risk ratios (RR), risk difference (RD) or mean difference (MD) along with 95% confidence intervals (CIs).
Twenty-one randomized controlled trials (RCTs) were selected for meta-analysis, with a total of 7,060 patients. Although there is a slightly lower risk of cecal intubation failure with the adjuvant of MEI (RD 3%; P < 0.00001) compared to the control group, the updated studies show no significant benefits. Similarly, the cecal intubation time, pain scores, and loop formation with the adjuvant of MEI did not show any advantages. However, considerable significant benefits were found in the subgroup of technically difficult colonoscopy and inexperienced colonoscopists. Moreover, MEI was associated with lower loop intubation time, lower abdominal compression times, and better lesion localization.
The clinical benefits of MEI could be exaggerated. However, MEI has considerable advantages in technically difficult colonoscopies, the assistance for inexperienced colonoscopists, loop resolving, and lesion localization.
磁内镜成像（MEI）被认为是一种辅助设备，可以提高结肠镜检查过程中的疗效和患者舒适度。
检索了几个电子数据库，以确定符合条件的研究。根据纳入研究的异质性，使用随机效应或固定效应模型计算合并的风险比（RR）、风险差（RD）或均数差（MD）及其 95%置信区间（CI）。
共纳入 21 项随机对照试验（RCT）进行荟萃分析，共有 7060 名患者。尽管与对照组相比，MEI 辅助下盲肠插管失败的风险略低（RD 3%；P<0.00001），但更新的研究并未显示出显著的获益。同样，MEI 辅助下盲肠插管时间、疼痛评分和圈形成也没有显示出任何优势。然而，在技术难度较大的结肠镜检查和经验不足的结肠镜检查中，发现了相当大的显著获益。此外，MEI 与较低的圈插管时间、较低的腹部压迫时间和更好的病变定位有关。
MEI 的临床获益可能被夸大了。然而，MEI 在技术难度较大的结肠镜检查中、对经验不足的结肠镜检查医生的辅助、解决圈形成问题和病变定位方面具有相当大的优势。
