Department of Orthopedics, Second Hospital of Xi'an Jiaotong University, Xi'an, China.
Department of Orthopaedic Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
J Orthop Surg (Hong Kong). 2020 Sep-Dec;28(3):2309499020965681. doi: 10.1177/2309499020965681.
This randomized controlled study was designed to compare the wound closure efficacy and safety of barbed suture in comparison to the conventional interrupted suture for total knee arthroplasty (TKA).
This multicenter, single-blind, randomized controlled trial enrolled 184 patients who underwent elective TKA between June 2017 and April 2018. The subjects were randomized between two groups. Surgical incision closure time was considered as the primary end point.
A total of 184 patients participated in this randomized controlled trial; 91 patients had wound closure that involved barbed suture and 93 patients underwent conventional treatment-that is interrupted suturing with nonbarbed sutures. The surgical incision closure time was shorter ( < 0.0001) in the barbed suture group compared with the control group (15.5 ± 4.88 vs. 20.9 ± 6.30 min). However, both groups were found to be equal in terms of the rate of postoperative complications.
Usage of the symmetric anchor designed barbed suture is safe, efficacious, and demonstrates a decrease in surgical incision closure time in patients undergoing TKA compared to interrupted closure using conventional sutures. Future studies are warranted to demonstrate clinical and economic benefits of barbed sutures.
本随机对照研究旨在比较带倒刺缝线与传统间断缝线在全膝关节置换术（TKA）中的伤口闭合效果和安全性。
这项多中心、单盲、随机对照试验纳入了 2017 年 6 月至 2018 年 4 月期间接受择期 TKA 的 184 例患者。将受试者随机分为两组。手术切口闭合时间为主要终点。
共有 184 例患者参与了这项随机对照试验；91 例患者的伤口闭合采用带倒刺缝线，93 例患者采用传统治疗——即非带倒刺缝线间断缝合。带倒刺缝线组的手术切口闭合时间明显短于对照组（<0.0001；15.5±4.88 比 20.9±6.30 min）。但是，两组患者的术后并发症发生率相当。
与间断缝合相比，使用对称锚定设计的带倒刺缝线在 TKA 患者中是安全、有效且可缩短手术切口闭合时间的。需要进一步研究来证明带倒刺缝线的临床和经济效益。
