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精神疾病与癌症手术患者自杀意念风险增加有关。

Mental illness is associated with increased risk of suicidal ideation among cancer surgical patients.

机构信息

Department of Surgery, The Ohio State University Wexner Medical Center and James Cancer Hospital and Solove Research Institute, Columbus, OH, USA.

Department of Surgery, The Ohio State University Wexner Medical Center and James Cancer Hospital and Solove Research Institute, Columbus, OH, USA.

出版信息

Am J Surg. 2021 Jul;222(1):126-132. doi: 10.1016/j.amjsurg.2020.10.028. Epub 2020 Oct 20.

DOI:10.1016/j.amjsurg.2020.10.028
PMID:33268055
Abstract

BACKGROUND

Mental illness and depression can be associated with increased risk of suicidal ideation (SI). We sought to determine the association between mental illness and SI among cancer surgical patients.

METHODS

Medicare beneficiaries who underwent resection of lung, esophageal, pancreatic, colon, or rectal cancer were analyzed. Patients were categorized as no mental illness, anxiety and/or depression disorders or bipolar/schizophrenic disorders.

RESULTS

Among 211,092 Medicare beneficiaries who underwent surgery for cancer, the rate of suicidal ideation was 270/100,000 patients. Antecedent mental health diagnosis resulted in a marked increased SI. On multivariable analysis, patients with anxiety alone (OR 1.49, 95%CI 1.04-2.14), depression alone (OR 2.60, 95%CI 1.92-3.38), anxiety + depression (OR 4.50, 95%CI 3.48-5.86), and bipolar/schizophrenia (OR 7.30, 95%CI 5.27-10.30) had increased odds of SI.

CONCLUSIONS

Roughly 1 in 370 Medicare beneficiaries with cancer who underwent a wide range of surgical procedures had SI. An antecedent mental health diagnosis was a strong risk factor for SI.

摘要

背景

精神疾病和抑郁症可能与自杀意念(SI)的风险增加有关。我们旨在确定癌症手术患者中精神疾病与 SI 之间的关联。

方法

对接受肺、食管、胰腺、结肠或直肠切除术的医疗保险受益患者进行分析。患者分为无精神疾病、焦虑和/或抑郁障碍或双相情感障碍/精神分裂症障碍。

结果

在接受癌症手术的 211092 名医疗保险受益患者中,自杀意念的发生率为 270/100000 例。先前的心理健康诊断导致自杀意念明显增加。在多变量分析中,仅患有焦虑症(OR 1.49,95%CI 1.04-2.14)、仅患有抑郁症(OR 2.60,95%CI 1.92-3.38)、焦虑+抑郁症(OR 4.50,95%CI 3.48-5.86)和双相情感障碍/精神分裂症(OR 7.30,95%CI 5.27-10.30)的患者发生 SI 的可能性增加。

结论

大约 1/370 名接受各种手术的癌症医疗保险受益患者有 SI。先前的心理健康诊断是 SI 的一个强危险因素。

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