• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

接受大隐静脉移植血管经皮冠状动脉介入治疗的急性冠状动脉综合征患者的炎症状态

Inflammatory Conditions in Acute Coronary Syndrome Patients Treated with Percutaneous Coronary Intervention of Saphenous Vein Graft.

作者信息

Cankurt Tayyar, Celik İbrahim E, Ozturk Selcuk, Maden Orhan

机构信息

Cardiology Clinic, Amasya University Sabuncuoglu Sereefeddin State Hospital, Ankara, Turkey.

Department of Cardiology, University of Health Sciences, Ankara Education and Research Hospital, Ankara, Turkey.

出版信息

Int J Angiol. 2020 Dec;29(4):237-244. doi: 10.1055/s-0040-1714751. Epub 2020 Aug 30.

DOI:10.1055/s-0040-1714751
PMID:33268974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7690989/
Abstract

The study aimed to evaluate the inflammatory blood parameters in acute coronary syndrome (ACS) patients with a history of coronary artery bypass graft (CABG) and treated with percutaneous coronary intervention (PCI) of saphenous vein graft (SVG). A total of 347 patients who underwent urgent SVG PCI with the diagnosis of ACS were included in the study. After the application of exclusion criteria, 79 patients were allocated into two groups, namely, successful PCI (  = 59) and unsuccessful PCI (  = 20), and included in the statistical analysis. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) levels were significantly higher in patients with unsuccessful SVG PCI. In the logistic regression analysis, PLR, C-reactive protein, and diabetes mellitus emerged as independent factors associated with unsuccessful SVG PCI. The area under the curve for PLR was 0.70 (95% confidence interval: 0.55-0.85,  = 0.006). The cut-off value of PLR (128.99) was associated with 70.0% sensitivity and 69.5% specificity. Elevated inflammatory status is associated with unsuccessful PCI of SVG in ACS patients. Increased PLR levels on admission is an independent predictor of this situation. This cheap and simple marker can help us to predict unsuccessful SVG PCI in ACS patients.

摘要

本研究旨在评估有冠状动脉旁路移植术(CABG)病史且接受大隐静脉桥血管(SVG)经皮冠状动脉介入治疗(PCI)的急性冠状动脉综合征(ACS)患者的血液炎症参数。共有347例诊断为ACS并接受紧急SVG PCI的患者纳入本研究。应用排除标准后,79例患者被分为两组,即PCI成功组(n = 59)和PCI失败组(n = 20),并纳入统计分析。SVG PCI失败患者的中性粒细胞与淋巴细胞比值(NLR)和血小板与淋巴细胞比值(PLR)水平显著更高。在逻辑回归分析中,PLR、C反应蛋白和糖尿病是与SVG PCI失败相关的独立因素。PLR的曲线下面积为0.70(95%置信区间:0.55 - 0.85,P = 0.006)。PLR的截断值(128.99)与70.0%的敏感性和69.5%的特异性相关。炎症状态升高与ACS患者SVG PCI失败相关。入院时PLR水平升高是这种情况的独立预测因素。这个廉价且简单的标志物可帮助我们预测ACS患者SVG PCI失败。

相似文献

1
Inflammatory Conditions in Acute Coronary Syndrome Patients Treated with Percutaneous Coronary Intervention of Saphenous Vein Graft.接受大隐静脉移植血管经皮冠状动脉介入治疗的急性冠状动脉综合征患者的炎症状态
Int J Angiol. 2020 Dec;29(4):237-244. doi: 10.1055/s-0040-1714751. Epub 2020 Aug 30.
2
Assessment of systemic immune-inflammation index as an independent surrogate biomarker of no-reflow phenomenon in acute coronary syndrome patients with coronary artery bypass grafting undergoing percutaneous coronary intervention of saphenous vein graft.评估全身免疫炎症指数作为行隐静脉移植血管经皮冠状动脉介入治疗的急性冠状动脉综合征冠状动脉搭桥患者无复流现象的独立替代生物标志物。
Eur Rev Med Pharmacol Sci. 2023 Mar;27(6):2394-2403. doi: 10.26355/eurrev_202303_31774.
3
Periprocedural and In-Hospital Outcomes Among Percutaneous Coronary Intervention in Saphenous Vein Graft: A Retrospective Observational Study at a Tertiary Care Hospital in South Asian Country.隐静脉桥血管经皮冠状动脉介入治疗的围手术期及住院期间结局:南亚某三级医疗中心的一项回顾性观察研究
Cureus. 2021 Apr 1;13(4):e14251. doi: 10.7759/cureus.14251.
4
Percutaneous Coronary Intervention of Saphenous Vein Graft.经皮冠状动脉介入治疗的隐静脉桥。
Circ Cardiovasc Interv. 2017 May;10(5). doi: 10.1161/CIRCINTERVENTIONS.117.004953.
5
Correlation of the Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) with Contrast-Induced Nephropathy in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Interventions.急性冠脉综合征患者接受经皮冠状动脉介入治疗时中性粒细胞与淋巴细胞比值(NLR)和血小板与淋巴细胞比值(PLR)与对比剂肾病的相关性
Cureus. 2020 Dec 3;12(12):e11879. doi: 10.7759/cureus.11879.
6
Comparison of clinical outcomes in patients presenting with an acute coronary syndrome due to stent thrombosis or saphenous vein graft occlusion and undergoing percutaneous coronary intervention.因支架血栓形成或隐静脉桥闭塞而出现急性冠状动脉综合征并接受经皮冠状动脉介入治疗的患者的临床结局比较。
Cardiovasc Revasc Med. 2015 Dec;16(8):441-6. doi: 10.1016/j.carrev.2015.10.002. Epub 2015 Oct 24.
7
Characteristics of Radial Artery Coronary Bypass Graft Failure and Outcomes Following Subsequent Percutaneous Coronary Intervention.经皮冠状动脉介入治疗后桡动脉冠状动脉旁路移植术失败的特点及结局。
JACC Cardiovasc Interv. 2023 Feb 27;16(4):457-467. doi: 10.1016/j.jcin.2022.11.035.
8
The Value of Inflammation Indexes in Predicting Patency of Saphenous Vein Grafts in Patients With Coronary Artery Bypass Graft Surgery.炎症指标在预测冠状动脉旁路移植术患者隐静脉移植血管通畅性中的价值
Cureus. 2021 Jul 26;13(7):e16646. doi: 10.7759/cureus.16646. eCollection 2021 Jul.
9
Saphenous Vein Graft Failure: From Pathophysiology to Prevention and Treatment Strategies.隐静脉移植物失败:从病理生理学到预防和治疗策略。
Circulation. 2021 Aug 31;144(9):728-745. doi: 10.1161/CIRCULATIONAHA.120.052163. Epub 2021 Aug 30.
10
One-year outcomes of percutaneous coronary intervention in native coronary arteries versus saphenous vein grafts in patients with prior coronary artery bypass graft surgery.经皮冠状动脉介入治疗在既往冠状动脉旁路移植术患者中的原生冠状动脉与隐静脉桥中的 1 年结果。
Cardiol J. 2022;29(3):396-404. doi: 10.5603/CJ.a2020.0131. Epub 2020 Oct 1.

引用本文的文献

1
Associations between the Platelet Lymphocyte Ratio and Albumin with Plaque Calcification in Patients with Acute Coronary Syndrome: An Optical Coherence Tomography Study.急性冠状动脉综合征患者血小板淋巴细胞比率和白蛋白与斑块钙化之间的关联:一项光学相干断层扫描研究
Rev Cardiovasc Med. 2025 Apr 27;26(4):28167. doi: 10.31083/RCM28167. eCollection 2025 Apr.
2
Reply to Letter to the Editor: 'Factors Influencing the Risk of No-Reflow Development'.致编辑信的回复:“影响无复流发生风险的因素”
Anatol J Cardiol. 2024 Mar 1;28(5):257-61. doi: 10.14744/AnatolJCardiol.2024.4226.
3
The stress hyperglycemic ratio can predict the no-reflow phenomenon following saphenous vein graft intervention in patients with acute coronary syndrome.应激性高血糖比值可预测急性冠脉综合征患者行隐静脉旁路移植介入术后无复流现象。
Acta Diabetol. 2024 Mar;61(3):333-341. doi: 10.1007/s00592-023-02201-0. Epub 2023 Nov 2.
4
Assessment of Inflammatory Hematological Ratios (NLR, PLR, MLR, LMR and Monocyte/HDL-Cholesterol Ratio) in Acute Myocardial Infarction and Particularities in Young Patients.评估炎症性血液学比值(NLR、PLR、MLR、LMR 和单核细胞/高密度脂蛋白胆固醇比值)在急性心肌梗死中的作用及在年轻患者中的特点。
Int J Mol Sci. 2023 Sep 21;24(18):14378. doi: 10.3390/ijms241814378.

本文引用的文献

1
Diagnostic and prognostic value of biomarkers in acute myocardial infarction.生物标志物在急性心肌梗死中的诊断和预后价值。
Postgrad Med J. 2019 Apr;95(1122):210-216. doi: 10.1136/postgradmedj-2019-136409. Epub 2019 Apr 4.
2
Biomarkers in acute myocardial infarction: current perspectives.急性心肌梗死中的生物标志物:当前观点
Vasc Health Risk Manag. 2019 Jan 17;15:1-10. doi: 10.2147/VHRM.S166157. eCollection 2019.
3
Are Pre and Postoperative Platelet to Lymphocyte Ratio and Neutrophil to Lymphocyte Ratio Associated with Early Postoperative AKI Following CABG?冠状动脉旁路移植术后血小板与淋巴细胞比值及中性粒细胞与淋巴细胞比值是否与术后早期急性肾损伤相关?
Braz J Cardiovasc Surg. 2018 May-Jun;33(3):233-241. doi: 10.21470/1678-9741-2017-0164.
4
Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis.中性粒细胞与淋巴细胞比值对急性ST段抬高型心肌梗死患者经皮冠状动脉介入治疗后的预测价值:一项荟萃分析
BMC Cardiovasc Disord. 2018 May 2;18(1):75. doi: 10.1186/s12872-018-0812-6.
5
Inflammation in Vein Graft Disease.静脉移植物疾病中的炎症
Front Cardiovasc Med. 2018 Jan 24;5:3. doi: 10.3389/fcvm.2018.00003. eCollection 2018.
6
The Role of Hematological Indices in Patients with Acute Coronary Syndrome.血液学指标在急性冠状动脉综合征患者中的作用。
Dis Markers. 2017;2017:3041565. doi: 10.1155/2017/3041565. Epub 2017 Oct 3.
7
The relationship between lymphocyte-to-monocyte ratio and saphenous vein graft patency in patients with coronary artery bypass graft.冠状动脉旁路移植术患者淋巴细胞与单核细胞比值与大隐静脉移植血管通畅性的关系
Biomark Med. 2017 Oct;11(10):867-876. doi: 10.2217/bmm-2017-0079. Epub 2017 Oct 4.
8
Neutrophils as protagonists and targets in chronic inflammation.中性粒细胞在慢性炎症中的主角和靶点。
Nat Rev Immunol. 2017 Apr;17(4):248-261. doi: 10.1038/nri.2017.10. Epub 2017 Mar 13.
9
Advanced glycation end products impair the functions of saphenous vein but not thoracic artery smooth muscle cells through RAGE/MAPK signalling pathway in diabetes.在糖尿病中,晚期糖基化终产物通过RAGE/MAPK信号通路损害隐静脉而非胸主动脉平滑肌细胞的功能。
J Cell Mol Med. 2016 Oct;20(10):1945-55. doi: 10.1111/jcmm.12886. Epub 2016 Jun 14.
10
Vein graft failure: from pathophysiology to clinical outcomes.静脉移植物失败:从病理生理学到临床结局。
Nat Rev Cardiol. 2016 Aug;13(8):451-70. doi: 10.1038/nrcardio.2016.76. Epub 2016 May 19.