Tobar Pool, Sanchez-Nadales Alejandro, Caldeira Elena, Saad Peguy
Department of Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USA.
Department of Infectious Diseases, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USA.
Oxf Med Case Reports. 2020 Nov 24;2020(11):omaa093. doi: 10.1093/omcr/omaa093. eCollection 2020 Nov.
Blastomyces dermatitidis is an endemic mold infection commonly seen in the midwestern of the USA and rarely affects pregnant women. The most common presentation is a pulmonary infection with variable degrees of severity. Of note, the clinical and radiographic findings of pulmonary blastomycosis can be mistaken for other pulmonary pathologies, thus earning the title of 'the great pretender'. The treatment of choice of infected pregnant patients is amphotericin B, which is known to produce electrolyte imbalances. However, it infrequently causes severe, prolonged and profound hypokalemia and hypomagnesemia. We present the case of a 27-year-old pregnant patient with pulmonary blastomycosis presenting with a lung mass suspicious of malignancy and treated with amphotericin B with subsequent prolonged refractory hypokalemia and hypomagnesemia. Keywords pulmonary blastomycosis pregnancy biopsy computed tomography angiography liposomal amphotericin B.
皮炎芽生菌是一种地方性霉菌感染，常见于美国中西部，很少影响孕妇。最常见的表现是不同严重程度的肺部感染。值得注意的是，肺芽生菌病的临床和影像学表现可能被误诊为其他肺部疾病，因此获得了“伪装大师”的称号。感染孕妇的首选治疗药物是两性霉素B，已知该药会导致电解质失衡。然而，它很少引起严重、持续且严重的低钾血症和低镁血症。我们报告一例27岁患有肺芽生菌病的孕妇病例，该患者表现为肺部有可疑恶性肿瘤的肿块，并接受了两性霉素B治疗，随后出现了持续的难治性低钾血症和低镁血症。关键词：肺芽生菌病；妊娠；活检；计算机断层血管造影；脂质体两性霉素B
