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急性肺芽生菌病的诊断延误与抗生素过度使用

Diagnostic Delay and Antibiotic Overuse in Acute Pulmonary Blastomycosis.

作者信息

Alpern Jonathan D, Bahr Nathan C, Vazquez-Benitez Gabriela, Boulware David R, Sellman Jonathan S, Sarosi George A

机构信息

Division of Infectious Disease & International Medicine, Department of Medicine,University of Minnesota, Minneapolis; Department of Medicine, Regions Hospital, St. Paul, Minnesota.

Division of Infectious Disease & International Medicine, Department of Medicine,University of Minnesota, Minneapolis; Division of Infectious Diseases, Department of Medicine, University of Kansas.

出版信息

Open Forum Infect Dis. 2016 Apr 19;3(2):ofw078. doi: 10.1093/ofid/ofw078. eCollection 2016 Apr.

DOI:10.1093/ofid/ofw078
PMID:27419155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4943562/
Abstract

The diagnosis of blastomycosis is often delayed. We identified 28 cases of pulmonary blastomycosis in a retrospective chart review. Most patients received multiple antibiotic courses before being diagnosed, and the sputum KOH smear was rarely used. Diagnostic delay can be decreased with higher suspicion for pulmonary blastomycosis and early use of the sputum KOH smear.

摘要

芽生菌病的诊断常常被延误。在一项回顾性病历审查中,我们识别出28例肺芽生菌病病例。大多数患者在被诊断之前接受了多个疗程的抗生素治疗,并且很少使用痰KOH涂片检查。提高对肺芽生菌病的怀疑度并早期使用痰KOH涂片检查可减少诊断延误。

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本文引用的文献

1
Community-acquired pneumonia.社区获得性肺炎
N Engl J Med. 2014 Oct 23;371(17):1619-28. doi: 10.1056/NEJMra1312885.
2
Incidence and trends of blastomycosis-associated hospitalizations in the United States.美国芽生菌病相关住院治疗的发病率及趋势。
PLoS One. 2014 Aug 15;9(8):e105466. doi: 10.1371/journal.pone.0105466. eCollection 2014.
3
The endemic mimic: blastomycosis an illness often misdiagnosed.地方性模仿病:芽生菌病——一种常被误诊的疾病
Trans Am Clin Climatol Assoc. 2014;125:188-202; discussion 202-3.
4
Endemic mycoses: overlooked causes of community acquired pneumonia.地方性真菌病:被忽视的社区获得性肺炎病因。
Respir Med. 2012 Jun;106(6):769-76. doi: 10.1016/j.rmed.2012.02.004. Epub 2012 Mar 3.
5
Clinical characteristics and outcomes in patients with pulmonary blastomycosis.肺芽生菌病患者的临床特征与预后
Mycopathologia. 2009 Mar;167(3):115-24. doi: 10.1007/s11046-008-9163-7. Epub 2008 Oct 19.
6
Clinical practice guidelines for the management of blastomycosis: 2008 update by the Infectious Diseases Society of America.芽生菌病管理临床实践指南:美国传染病学会2008年更新版
Clin Infect Dis. 2008 Jun 15;46(12):1801-12. doi: 10.1086/588300.
7
The epidemiology of blastomycosis in Illinois and factors associated with death.伊利诺伊州芽生菌病的流行病学及与死亡相关的因素。
Clin Infect Dis. 2005 Dec 15;41(12):e107-11. doi: 10.1086/498152. Epub 2005 Nov 9.
8
Antigen assay with the potential to aid in diagnosis of blastomycosis.有助于诊断芽生菌病的抗原检测。
J Clin Microbiol. 2004 Oct;42(10):4873-5. doi: 10.1128/JCM.42.10.4873-4875.2004.
9
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Semin Respir Infect. 1997 Sep;12(3):219-28.