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非手术性鼻部整形术(注射填充剂):2488 例手术的安全性评估。

Nonsurgical Rhinoplasty Using Injectable Fillers: A Safety Review of 2488 Procedures.

机构信息

Westside Aesthetics, Los Angeles, California, USA.

Department of Medicine, UCLA, Los Angeles, California, USA.

出版信息

Facial Plast Surg Aesthet Med. 2021 Jan-Feb;23(1):6-11. doi: 10.1089/fpsam.2020.0291. Epub 2020 Dec 2.

DOI:10.1089/fpsam.2020.0291
PMID:33270519
Abstract

Injectable fillers are used worldwide to improve the appearance of the nose by nonsurgical methods. The procedure is not without risks, as blindness and skin necrosis have been reported as a consequence of filler injections in the nose. To determine an overall adverse event (AE) rate for the nonsurgical rhinoplasty (NSR) procedure and to assess whether previous surgical rhinoplasty increases the odds of an AE. A retrospective chart review of 2275 patients and 2488 NSR procedures for a 10-year period from a single physician injector was conducted. The overall procedural AE rate was 7.6%, with five cases (0.20%) considered serious (ischemia and necrosis). Previous surgical rhinoplasty patients had a greater AE rate (10.8%) than those patients without previous surgery (7.4%), with a significant odds ratio of 1.51 (95% confidence interval: 1.03-2.18);  = 0.032. Injecting the tip and sidewall of the nose had the highest AE rates for both categories of patients. NSR is a relatively safe procedure with the majority of AEs common injection site reactions. Patients with previous surgical rhinoplasty demonstrated significantly increased odds of an AE potentially due to surgical changes in anatomy.

摘要

注射填充剂已在全球范围内被用于通过非手术方法改善鼻子的外观。但该操作并非没有风险,因为据报道,填充物注射到鼻子中会导致失明和皮肤坏死。本研究旨在确定非手术隆鼻(NSR)手术的总体不良事件(AE)发生率,并评估先前的手术隆鼻是否会增加 AE 的几率。回顾性分析了一名医生在 10 年内对 2275 名患者和 2488 例 NSR 手术进行的图表。总的手术 AE 发生率为 7.6%,其中 5 例(0.20%)被认为是严重的(缺血和坏死)。与无既往手术史的患者(7.4%)相比,有既往手术隆鼻史的患者 AE 发生率更高(10.8%),其优势比为 1.51(95%置信区间:1.03-2.18);=0.032。对于这两类患者,鼻尖和鼻侧壁的注射均具有最高的 AE 发生率。NSR 是一种相对安全的手术,大多数 AE 是常见的注射部位反应。有既往手术隆鼻史的患者 AE 的发生几率显著增加,这可能是由于解剖结构的手术改变所致。

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