Scarano Antonio, Sbarbati Andrea, Amuso Domenico, Amore Roberto, Tari Segio Rexhep, Alla Iris
Department of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, Via Dei Vestini 31, 66100, Chieti, Italy.
Department of Neurosciences, School of Medicine, Biomedicine and Movement Sciences, Anatomy and Histology Section, University of Verona, Verona, Italy.
Aesthetic Plast Surg. 2025 Jan;49(1):87-97. doi: 10.1007/s00266-024-04197-6. Epub 2024 Jun 28.
Projection and upper rotation to the tip is fundamental in the nasal rejuvenation, as a matter of fact the tip is the most important and has strongly effects on the improve appearance and quality of life. The aim of the present study was to evaluate reshaping the tip of the nose by cross-linked hyaluronic acid using Italian technique.
In a period between November 2019 and 2023, a total of one hundred and forty healthy, 95 females and 45 man patients, were performed with a mean age 44±5 (age range: 31-52 years old) affected by tip of congenital (22) or ageing nose hypotonia (118), and reduced volume that need of an elevation of the nose tip. The anatomic markers have been considered for the anthropometric measurements after the filler rhinoplasty. Two infiltrations were performed, one in the infiltration into the antero-caudal access over the columella produce upward rotation of the tip of the nose and second infiltration into the antero-superior access produce the projection of the tip of the nose. Medical device used in the study was Neofound STRUCT LIDO (LOVE COSMEDICAL srls-Via Toniolo 9, 57022 Castagneto Carducci, ITALY) containing sodium hyaluronate/hyaluronic acid high molecular weight (1.500<HA<2.000 KDA) 24%, sodium hyaluronate/hyaluronic acid low molecular weight (155<HA<230 KDA) 9%, niacinamide, glycine, proline, BDDE, and lidocaine chlorhydrate 3%.
The effect on the upward rotation of the tip nose was evaluated using Global Aesthetic Improvement Scale and morphometric evaluation. All the subjects showed at least 2-3 grade improvement in GAIS score after HA filler injection. The analysis of patient satisfaction after the last follow-up visits clearly demonstrated good results. A significant morphometric difference was detected comparing the T and T (p<0,0001), while no difference was present comparing T and T means (p=0.11). The outcome of the present clinical study gives greater projection and upper rotation to the tip with great gratification of the patients and the surgeon. An augmentation of the tip nose with hyaluronic acid filler produces a rejuvenation of the nose area resulted in a more youthful appearance. No adverse event was observed. In 35 patients, additional HA infiltration had to be performed after 2 weeks.
In conclusion, the Italian technique descripted in the present paper is safe, simply, and efficacious for rejuvenation of the nose, with elevated levels of patient satisfaction.
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鼻尖的突出度和上旋是鼻整形术的基本要素,事实上,鼻尖是最重要的,对改善外观和生活质量有很大影响。本研究的目的是评估使用意大利技术通过交联透明质酸重塑鼻尖。
在2019年11月至2023年期间,共对140名健康患者进行了手术,其中95名女性和45名男性,平均年龄44±5岁(年龄范围:31 - 52岁),这些患者患有先天性鼻尖低平(22例)或衰老导致的鼻尖低平(118例),且鼻尖体积减小需要抬高。在填充式鼻整形术后,考虑解剖标志进行人体测量。进行了两次注射,一次是在鼻小柱上的前尾侧入路注射,使鼻尖向上旋转,第二次是在前上入路注射,使鼻尖突出。本研究中使用的医疗器械是Neofound STRUCT LIDO(LOVE COSMEDICAL srls - Via Toniolo 9, 57022 Castagneto Carducci, ITALY),其含有24%的高分子量透明质酸钠/透明质酸(1500 < HA < 2000 KDA)、9%的低分子量透明质酸钠/透明质酸(155 < HA < 230 KDA)、烟酰胺、甘氨酸、脯氨酸、BDDE和3%的盐酸利多卡因。
使用全球美学改善量表和形态测量评估来评价鼻尖向上旋转的效果。所有受试者在注射透明质酸填充剂后GAIS评分至少提高了2 - 3级。最后一次随访后对患者满意度的分析清楚地显示出良好的效果。比较T和T时检测到显著的形态测量差异(p < 0.0001),而比较T和T均值时没有差异(p = 0.11)。本临床研究的结果使鼻尖有更大的突出度和上旋,患者和外科医生都非常满意。用透明质酸填充剂增加鼻尖高度可使鼻区年轻化,外观更显年轻。未观察到不良事件。35名患者在2周后需要额外注射透明质酸。
总之,本文所述的意大利技术对于鼻部年轻化是安全、简单且有效的,患者满意度较高。
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