Paul E
Hautklinik, Klinikum Justus-Liebig-Universität Giessen.
Z Hautkr. 1987;62 Suppl 1:79-87.
Which skin reactions, with allergic or pseudo-allergic mechanism, are actuated by food? Contact urticaria or "forme-fruste-anaphylaxis" is the most common. Tests, using purchasable allergen extracts, mostly produce negative results, due to inadequate natural identity. Therefore, scratchtests with the natural antigens are necessary. Apart from the acute and chronic urticaria, classic other reaction types (Coombs and Gell) within the scope of real food allergy are also present (allergic vasculitis from meat containing penicillin, thrombocyopenic purpura after taking aspirin or quinine); cellular immune reactions to food and its components are also not uncommon. The importance of natural salicylate for the aetiopathogenesis of chronic urticaria has not yet been ascertained; nevertheless, a suitable diet is recommended on the understanding that degranulation of the mast cells, possibly due to subclinical stimuli, is triggered off.
哪些由食物引发的、具有过敏或类过敏机制的皮肤反应?接触性荨麻疹或“顿挫型过敏反应”最为常见。使用可购买的过敏原提取物进行检测,大多会得出阴性结果,这是因为天然成分不充分。因此,使用天然抗原进行划痕试验很有必要。除了急性和慢性荨麻疹外,在真正的食物过敏范围内还存在其他经典反应类型(库姆斯和盖尔分类)(含青霉素肉类引发的过敏性血管炎、服用阿司匹林或奎宁后出现的血小板减少性紫癜);对食物及其成分的细胞免疫反应也并不罕见。天然水杨酸盐在慢性荨麻疹病因发病机制中的重要性尚未确定;然而,建议采用适当的饮食,基于这样的理解,即肥大细胞的脱颗粒可能是由亚临床刺激引发的。