Department of Research, Shriners Hospitals for Children (Dr Gannotti and Ms Liquori), Springfield, Massachusetts; Department of Rehabilitation Services (Dr Gannotti), University of Hartford, West Hartford, Connecticut; Department of Allied Health Services (Ms Thorpe), The University of North Carolina at Chapel Hill, North Carolina; Department of Physical Therpay (Ms Fuchs), Indiana University-Purdue University, Indianapolis, Indiana.
Pediatr Phys Ther. 2021 Jan 1;33(1):50-56. doi: 10.1097/PEP.0000000000000765.
Individuals with cerebral palsy (CP), ambulatory or not, have less bone strength and density than their peers. Aging individuals with CP are at a higher risk for nontraumatic fractures, progressive deformity, pain, and spinal stenosis. Critical periods for skeletal formation are during prepuberty and adolescence. Applying mechanostat theory to exercise design for individuals with CP may be beneficial.
Principles of mechanostat theory, particularly the osteogenic index, is applied to guide the design of exercise programs based on varying levels of physical capacity.
Recommendations are made for optimizing dosing of a variety of interventions for improving bone health among individuals with CP based on mechanostat theory with specific type, number of repetitions, and frequency.
Researchers and clinicians are called to action to consider the role of exercise throughout the lifespan for all individuals with CP, regardless of level of severity.
有脑瘫（CP）的个体，无论是否能行走，其骨骼强度和密度均低于同龄人。患有脑瘫的老年个体发生非外伤性骨折、进行性畸形、疼痛和椎管狭窄的风险更高。骨骼形成的关键时期是青春期前和青春期。将机械压力理论应用于脑瘫患者的运动设计可能是有益的。
将机械压力理论的原理，特别是成骨指数，应用于运动方案的设计中，根据不同的身体能力水平进行指导。
根据机械压力理论，针对改善脑瘫患者骨骼健康的各种干预措施，提出了优化剂量的建议，具体包括干预的类型、重复次数和频率。
研究人员和临床医生应采取行动，考虑到在整个生命周期中，无论脑瘫的严重程度如何，运动对于所有脑瘫患者的作用。
