Shriners Hospitals for Children (Ms Liquori and Dr Gannotti), Springfield, Massachusetts; Department of Rehabilitation Services (Dr Gannotti), University of Hartford, West Hartford, Connecticut; Department of Allied Health Services (Dr Thorpe), University of North Carolina, Chapel Hill, North Carolina; Department of Rehabilitation Sciences (Dr Fuchs), Indiana University-Purdue University, Indianapolis, Indiana.
Pediatr Phys Ther. 2022 Apr 1;34(2):163-170. doi: 10.1097/PEP.0000000000000878.
A systematic review evaluated exercise parameters and ages that produced the most improvement in bone among individuals with cerebral palsy (CP) ages 3 to 21 years.
PubMed, Scopus, Ebscohost, and Web of Science identified potential articles. Covidence was used to identify eligible citations and assess bias. The osteogenic index (OI) was used to evaluate intervention parameters.
The database search identified 312 citations. Twelve full-text articles were included. A 1-hour calisthenic exercise program performed 2 to 3 times a week for 8 months targeting each body region had the highest effect size and a substantial OI. Most of the interventions reviewed had low OIs. Activities of longer duration and greater intensity had greater OIs and prepubertal age-enhanced treatment effects.
Bone interventions for individuals with CP have low OIs, and principles of mechanostat theory should be applied to exercise dosing.
系统评价评估了 3 至 21 岁脑瘫（CP）患者中哪些运动参数和年龄能最大程度地改善骨骼。
通过 PubMed、Scopus、Ebscohost 和 Web of Science 确定潜在文章。Covidence 用于识别合格的引文并评估偏倚。使用成骨指数（OI）来评估干预参数。
数据库搜索确定了 312 条引文。纳入了 12 篇全文文章。每周进行 2 到 3 次，每次 1 小时的健身操运动方案，针对每个身体区域，效果最大，成骨指数也较高。大多数综述的干预措施的成骨指数都较低。持续时间较长和强度较大的活动具有更高的成骨指数，且青春前期年龄能增强治疗效果。
针对 CP 患者的骨骼干预措施的成骨指数较低，应将机械压力理论的原则应用于运动剂量。
