Controlled and cellulose eco-friendly synthesis and characterization of BiOCO quantum dot nanostructures (QDNSs) and drug delivery study.

This work aimed to prepare solvent-free or green BiOCO for quantum dot nanostructures (QDNSs) based on cellulose as a stabilizer and green capping agent to sorafenib delivery for liver targeting. Because the walnut tree is one of the most abundant trees in Iran, it was tried to synthesize BiOCO QDNSs using a walnut skin extract. The saturation magnetization for BiOCO QDNSs was calculated to be 68.1. Also, the size of products was measured at around 60-80 nm with the Debye-Scherrer equation. Moreover, the morphology, functional groups, and crystallography of the BiOCO nanoparticles were investigated using atomic force microscopy, scanning electron microscopy, vibrating-sample magnetometer, and Uv-vis spectroscopy. The results demonstrated that BiOCO QDNSs have opto-magnetic properties and they can be suggested as the candidate materials for the sorafenib delivery on the liver tissue. The optical band gap estimated for BiOCO QDNSs was found to be red-shift from 3.22 eV. This study suggests the preparation of the BiOCO QDNSs based on cellulose as new opto-magnetic materials at different temperatures of 180 °C, 200 °C, 220 °C, and 240 °C for sorafenib delivery as a type of biological therapy drug.