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体内研究二极管激光在非手术牙周治疗中对红色复合体细菌的应用:一项分口随机对照试验。

In vivo investigation of diode laser application on red complex bacteria in non-surgical periodontal therapy: a split-mouth randomised control trial.

机构信息

Faculty of Dentistry, Oral Medicine and Periodontics, University of the Western Cape, Fransie van Zijl drive, Cape Town, 7505, South Africa.

Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Oral and Maxillofacial Pathology, University of the Western Cape, Cape Town, South Africa.

出版信息

Sci Rep. 2020 Dec 4;10(1):21311. doi: 10.1038/s41598-020-78435-7.

Abstract

Assessment of the efficacy of a single 810 nm diode laser application as an adjunctive treatment modality during the first intervention of non-surgical periodontal therapy (NPT). 25 patients diagnosed with chronic periodontitis underwent a split-mouth randomised control trial. The periodontal pockets of the test quadrants were treated with an 810 nm diode laser as an adjunct to NPT (Picasso GaAlAs; AMD Lasers). The laser was set at 1.0 W continuous wave, 400 µm tip, 796 W/cm peak power density and a 32 J/cm energy density. Therapeutic outcomes were evaluated based on the clinical parameters, which included probing pocket depth, recession, clinical attachment level, full mouth plaque score, full mouth bleeding on probing and tooth mobility. The baseline bacterial collection was completed from the periodontal pockets and then re-evaluated at 6 weeks. Clinical parameters demonstrated no statistical difference, with the exception of a statistically significant (P < 0.05) reduction in bleeding on probing for the test side. The test side resulted in a statistical increase of Capnocytophaga species and Treponema denticola. The single application of the diode laser did not significantly improve the bacterial nor the clinical parameters in patients with chronic periodontitis.Trial registration number: PACTR201909915338276.

摘要

评估 810nm 半导体激光单次应用作为非手术性牙周治疗(NPT)首次介入的辅助治疗方法的疗效。25 名慢性牙周炎患者接受了一项分侧随机对照试验。试验象限的牙周袋采用 810nm 半导体激光作为 NPT 的辅助治疗(Picasso GaAlAs;AMD Lasers)。激光设置为 1.0W 连续波、400µm 探头、796W/cm² 峰值功率密度和 32J/cm² 能量密度。根据临床参数评估治疗效果,包括探诊袋深度、退缩、临床附着水平、全口菌斑评分、全口探诊出血和牙齿松动度。基线细菌采集来自牙周袋,然后在 6 周时重新评估。临床参数除探诊出血有统计学差异(P<0.05)外,无统计学差异。试验侧的探诊出血有统计学显著减少。试验侧导致 Capnocytophaga 种和 Treponema denticola 的统计学增加。单次半导体激光应用并未显著改善慢性牙周炎患者的细菌和临床参数。试验注册号:PACTR201909915338276。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cb5/7718262/08f428a1a8c5/41598_2020_78435_Fig1_HTML.jpg

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