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抗阻训练联合常规治疗对急性烧伤成人患者疗效的随机对照试验

The efficacy of resistance training in addition to usual care for adults with acute burn injury: A randomised controlled trial.

机构信息

State Adult Burns Service, South Metropolitan Area Health Service, Fiona Stanley Hospital, Murdoch, Western Australia, Australia; School of Physiotherapy, University of Notre Dame Australia, Fremantle, Western Australia, Australia; Fiona Wood Foundation, Murdoch, Western Australia, Australia.

School of Physiotherapy, University of Notre Dame Australia, Fremantle, Western Australia, Australia.

出版信息

Burns. 2021 Feb;47(1):84-100. doi: 10.1016/j.burns.2020.03.015. Epub 2020 Dec 4.

DOI:10.1016/j.burns.2020.03.015
PMID:33280953
Abstract

Resistance training immediately after a burn injury has not been investigated previously. This randomised, controlled trial assessed the impact of resistance training on quality of life plus a number of physical, functional and safety outcomes in adults with a burn injury. Patients were randomly assigned to receive, in addition to standard physiotherapy, four weeks of high intensity resistance training (RTG) or sham resistance training (CG) three days per week, commenced within 72h of the burn injury. Outcome data was collected at six weeks, three and six months after burn injury. Quality of life at 6 months was the primary endpoint. Data analysis was an available cases analysis with no data imputed. Regression analyses were used for all longitudinal outcome data and between-group comparisons were used for descriptive analyses. Forty-eight patients were randomised resistance training (RTG) (n=23) or control group (CG) (n=25). The RTG demonstrated improved outcomes for the functional domain of the Burn Specific Health Scale-Brief (p=0.017) and the Quick Disability of Arm Shoulder and Hand (p<0.001). Between group differences were seen for C-reactive protein and retinol binding protein (p=0.001). Total quality of life scores, lower limb disability, muscle strength and volume were not seen to be different between groups (p>0.05). Resistance training in addition to usual rehabilitation therapy showed evidence of improving functional outcomes, particularly in upper limb burn injuries. Additionally, resistance training commenced acutely after a burn injury was not seen to be harmful to patients.

摘要

先前并未研究过烧伤后立即进行抗阻训练。这项随机对照试验评估了抗阻训练对烧伤成人生活质量以及多项身体功能和安全性结果的影响。患者被随机分配,除了标准物理治疗外,还接受四周的高强度抗阻训练(RTG)或假抗阻训练(CG),每周三次,在烧伤后 72 小时内开始。在烧伤后 6 周、3 个月和 6 个月收集结果数据。6 个月时的生活质量是主要终点。数据分析采用可用病例分析,未进行数据插补。回归分析用于所有纵向结果数据,组间比较用于描述性分析。48 名患者被随机分配至抗阻训练组(RTG)(n=23)或对照组(CG)(n=25)。RTG 显示烧伤特异性健康量表-简短功能域(p=0.017)和快速上肢手部功能测试(p<0.001)的结果有所改善。C 反应蛋白和视黄醇结合蛋白之间存在组间差异(p=0.001)。组间在总生活质量评分、下肢残疾、肌肉力量和体积方面无差异(p>0.05)。除了常规康复治疗外,抗阻训练显示出改善功能结果的证据,特别是在上肢烧伤中。此外,烧伤后立即开始抗阻训练对患者没有危害。

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